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- 文献和实验
- 技术资料
- 保存条件：
4°C, stored under nitrogen
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
2173232-79-4
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥3850.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥1590.0 |
| 规格： | 5 mg | 产品价格： | ￥3500.0 |
| 规格： | 10 mg | 产品价格： | ￥5500.0 |
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LOM612
CAS No. : 2173232-79-4
MCE 国际站：LOM612
产品活性：LOM612 有效对 FOXO 胞质-胞核穿梭进行定位，在 U2fox RELOC 细胞中 EC50 值为 1.5 μM。
研究领域：Others
作用靶点：Others
In Vitro: LOM612 potently activates nuclear translocation of FOXO with an EC50 value of 1.5 μM, and this effect is independent of CRM-1. LOM612 effectively induces translocation of endogenous FOXO3a and FOXO1, and increases the expression of the FOXO target genes p27 and FasL. LOM612 shows no effect on the nuclear export of endogenous NFKB2 transcription factor in U2OS cells. LOM612 is cytotoxic to HepG2 cells, with an IC50 value of 0.64 μM, and does not sensitize non-cancer THLE2 cells (IC50, 2.76 μM).
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文献和实验An ELISA Lab-on-a-Chip (ELISA-LOC)
Laminated object manufacturing (LOM) technology using polymer sheets is an easy and affordable method for rapid prototyping of Lab-on-a-Chip (LOC) systems. It has recently been used to fabricate a miniature 96 sample ELISA lab-on-a-chip
Charged-Coupled Device (CCD) Detectors for Lab-on-a Chip (LOC) Optical Analysis
detection. The LOC used for this detection system was fabricated with laminated object manufacturing (LOM) technology, and was designed to detection activity of botulinum neurotoxin serotype A (BoNT-A) using a fluorogenic peptide substrate (SNAP
an endogenously expressed hybrid transcription factor, which positively regulates the expression of the gene of interest (Aoyama and Chua, Plant J 11:605–612, 1997). We have developed Arabidopsis plants using this inducible system to drive expression
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