Product overview
Description Anti-TSHR rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human TSHR
Reactivity Human
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol TSHR
Full name thyroid stimulating hormone receptor
Synonyms LGR3; CHNG1; hTSHR-I
Swissprot P16473
Target Background
The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.