Benzamidine was used in the preparation of heparan sulfate-rich proteoglycan from mouse mammary epithelial cells[2]. It has been used to prevent enzymatic degradation during the purification procedure of bovine factor XII (Hageman factor)[1].
Biochem/physiol Actions
Benzamidine is an inhibitor of plasmin and has been used in the radioimmunoassay of glucagon in human plasma[4]. It prevents the destruction of Thyrotropin-releasing hormone (TRH) added to whole blood in vitro before radioimmunoassay of TRH[3].