重组小鼠L-乳酸脱氢酶(LDHA)

特别提示：包括重组小鼠L-乳酸脱氢酶(LDHA)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠L-乳酸脱氢酶(LDHA)
英文名称：Recombinant Mouse L-lactate dehydrogenase
产品货号：JN1284
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met1-Phe332在C端含有His标签。

LDHA质量控制：＞95%(还原性SDS-PAGE)

LDHA制剂：液体

LDHA保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于LDHA：
Mouse Lactate dehydrogenase A (LDHA) is a member of the LDH/MDH superfamily and LDH family. LDHA catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumours. It has also been shown that LDHA plays an important role in the development, invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria.

除了重组小鼠L-乳酸脱氢酶(LDHA),，我公司还供应以下相关产品：



名称：重组人结缔组织生长因子(CTGF)(Glu27-Ala180)
货号：JN0276
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Glu27-Ala180表达纯化而来。

CTGF/CCN2质量控制：＞95%(还原性SDS-PAGE)。

CTGF/CCN2制剂：冻干品

CTGF/CCN2保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

CTGF/CCN2复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于CTGF/CCN2：
CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT), a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component).

名称：重组人淋巴细胞胞浆蛋白2(LCP2)
货号：JN1213
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Pro533在N端含T7标签，C端含有His标签。

LCP2质量控制：＞95%(还原性SDS-PAGE)

LCP2制剂：液体

LCP2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于LCP2：
Lymphocyte cytosolic protein 2(LCP2)contains a SAM domain and a SH2 domain. It is highly expressed in spleen, thymus and peripheral blood leukocytes, T-cell and monocytic cell lines, but expressed at lower level in B-cell lines. LCP2 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. It is phosphorylated after T-cell receptor activation by ZAP70, ITK and TXK, which leads to the up-regulation of Th1 preferred cytokine IL-2 during post-translational modification. Studies using LCP2-deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.