重组人酪氨酸蛋白激酶BLK

特别提示：包括重组人酪*酸蛋白激酶BLK在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人酪*酸蛋白激酶BLK
英文名称：Recombinant Human Tyrosine-Protein Kinase BLK
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Gly2-Pro505在C端含有His标签。

BLK质量控制：＞95%(还原性SDS-PAGE)

BLK制剂：液体

BLK保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于BLK：
Tyrosine-Protein Kinase Blk (BLK) contains one protein kinase domain, one SH2 domain and one SH3 domain. BLK is a non-receptor tyrosine kinase, which is involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulines and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Defects in BLK are a cause of maturity-onset diabetes of the young type 11 (MODY11).