关键词:唾液外泌体纯化试剂盒(提取试剂盒),Saliva Exosome Purification Kit,唾液外泌体纯化试剂盒
产品名称:唾液外泌体纯化试剂盒(提取试剂盒)-Saliva Exosome Purification Kit
产品货号:NGB-65300
产品规格:50Preps
背景资料:无内容
保存建议:唾液外泌体纯化试剂盒(提取试剂盒)-Saliva Exosome Purification Kit溶液密封室温(15-25°C)保存,未开封至少保存2年。
产品描述:Exosomes are 40 - 150 nm membrane vesicles which are secreted by most cell types. Exosomes can be found in plasma, serum, saliva, urine, amniotic fluid and malignant ascite fluids, among other biological fluids. Evidence has been accumulating recently that these vesicles act as cellular messengers, conveying information to distant cells and tissues within the body. The exosomes contain cell-specific proteins, lipids and RNAs, which are transported to other cells, where they can alter function and/or physiology. These exosomes may play a functional role in mediating adaptive immune responses to infectious agents and tumours, tissue repair, neural communication and transfer of pathogenic proteins. Recent work has demonstrated the presence of distinct subsets of microRNAs within exosomes and other extracellular vesicles (EVs) which depend upon the tumour cell type from which they are secreted. For this reason exosomal RNA may serve as biomarkers for various diseases including cancer. Another subset of RNA that is found in saliva is the free-circulating RNA (fc-RNA). These fc-RNA are usually protein-bound RNA that are leaked from cells either during apoptosis or necrosis. As the RNA molecules encapsulated within exosomes or bound to proteins (fc-RNA) are protected from degradation by RNAses, they can be efficiently recovered from biological fluids such as saliva. In general, these two RNA groups contain valuable information for the discovery of biomarkers that can help with early detection of certain cancer types and for monitoring the disease status.Norgen’s Saliva Exosome Purification Kit allows for the purification of saliva exosomes from 500 μL to 2 mL of fresh saliva samples or saliva samples collected using Norgen's Saliva Exosome Collection and Preservation Kit (Cat 65400). This kit also allows for the purification of intact extracellular vesicles (EVs) from different saliva sample volumes, and these EVs are ready for any downstream application. The purification is based on Norgen’s proprietary resin. These kits provide a clear advantage over other available kits in that they do not require any special instrumentation, precipitation reagents or any protease treatments. More importantly, the purified exosomes will not be contaminated with any other RNA-bound proteins that may contaminate your exosomal RNA, which is essential if studying exosomal RNA gene expression.
点击:唾液外泌体纯化试剂盒(提取试剂盒)-Saliva Exosome Purification Kit查看更详细产品说明,更多应用、储存、价格、货期等信息请致电垂询艾美捷科技有限公司。更多Norgen Biotek公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
Norgen Biotek成立于1998年,公司总部位于加拿大,是一家著名全球化生物技术公司,基于专利的碳化硅膜纯化技术和无苯酚专利配方,生产高品质的核酸和蛋白质纯化及富集产品用于研究和诊断。Norgen Biotek 在2003年获得加拿大国家研究委员会颁发的科技创新奖,是一家致力于样品制备并获得ISO 9001(产品质量)、ISO 13485(产品可用于商业化的医疗设备,包括用于体外诊断领域)和ISO 15189(可用于临床检测机分子诊断领域的研发能力)认证的生物科技公司。目前该公司的产品多达700余种,提供的样品制备试剂盒,应用于基因组和蛋白组等不同的领域。其产品主要覆盖包括各种标本类型的DNA,RNA和蛋白质的纯化富集,从活检样本(包括尿液,血浆,血清和血液)中纯化RNA和DNA,全系列的PCR试剂、缓冲液、分子量ladder和塑料过滤装置。
艾美捷科技有限公司,通过提供完整的产品和服务体系、便利的客户关系和供应链管理,为生命科学研究工作者提供整体打包方案。我们的企业的核心价值观:“学习、创新、合作、卓越"。作为一家具有尖端的技术实力、的经营管理水平和完善的市场销售体系的生物高科技企业,总部位于武汉光谷高新技术开发区,服务面向全国。艾美捷科技是集进口试剂、实验室耗材销售、技术服务与合约开发为一体的专业化高科技公司,为用户提供最前沿的专业资讯、完备的产品、整合的解决方案,及优质的物流服务。为了更好的服务客户,公司组建了一支经验丰富的研发团队-艾美捷生物技术中心,进入研发生产阶段,将更优质的产品推荐给国内生物领域的同仁们!