Detects human Cornulin in direct ELISAs and Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human Cornulin
Met1-Ser140
Accession # Q9UBG3
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Western Blot
0.1 µg/mL
Background: Cornulin
Cornulin, the product of the C1orf 10 gene found in the epidermal differentiation complex (EDC), is a 70 kDa protein that is expressed primarily in the upper layers of differentiated squamous tissues. It is a member of the “fused gene” family and contains two EF-hand Ca2+-binding domains in its amino-terminal region and two Thr/Glu-rich repeats in its C-terminal region. Over the region used as the immunogen, human and mouse Cornulin share 73% amino acid sequence identity.