重组人WDYHV1

特别提示：包括重组人WDYHV1在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人WDYHV1
英文名称：Recombinant Human Protein N-terminal glutamine amidohydrolase
产品货号：JN1389
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Cys205在N端带有GST标签。

WDYHV1质量控制：＞95%(还原性SDS-PAGE)

WDYHV1制剂：液体

WDYHV1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于WDYHV1：
Human protein N-terminal glutamine amidohydrolase (WDYHV1) is an enzyme that in humans is encoded by the WDYHV1 gene, belongs to the NTAQ1 family.WDYHV1 mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, which is an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. However,it does not act on substrates with internal or C-terminal glutamine andnon-glutamine residues in any position. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.

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