重组小鼠神经生长因子受体(NGF-R)(TNFRSF16)

特别提示：包括重组小鼠神经生长因子受体(NGF-R)(TNFRSF16)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠神经生长因子受体(NGF-R)(TNFRSF16)
英文名称：Recombinant Mouse Nerve Growth Factor Receptor
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gly20-Asn243在C端带有Fc标签。

NGF R/TNFRSF16 质量控制：＞95%(还原性SDS-PAGE)

NGF R/TNFRSF16 制剂：冻干品

NGF R/TNFRSF16 保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

NGF R/TNFRSF16 复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于NGF R/TNFRSF16 ：
Mouse Tumor necrosis factor receptor superfamily member 16(TNFRSF16) is a single-pass type I membrane protein which contains 1 death domain and 4 TNFR-Cys repeats. It has low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. It can mediate cell survival as well as cell death of neural cells. TNFRSF16 plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. It binds to rabies virus glycoprotein Gs. Necessary for the circadian oscilllation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.