- 询价
- 上海博湖
- BH-K20036
- 进口、国产
- 2025年06月26日
- WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
- 详见说明书
- 详见说明书
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- 详细信息
- 技术资料
- 抗体名：
1型神经纤维瘤抗体图片
- 抗体英文名：
Anti-NF1/Neurofibromin 1
- 靶点：
详见说明书
- 浓度：
1mg/1ml
- 应用范围：
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
- 宿主：
详见说明书
- 供应商：
上海博湖
- 库存：
大量
- 级别：
详见说明书
- 目录编号：
详见说明书
- 抗原来源：
Rabbit
- 保质期：
详见说明书
- 适应物种：
详见说明书
- 标记物：
详见说明书
- 克隆性：
多克隆
- 保存条件：
Store at -20 °C
- 形态：
详见说明书
- 亚型：
IgG
- 免疫原：
KLH conjugated synthetic peptide derived from human Neurofibromin 1 C-terminus
- 规格：
0.2ml/200μg
中文名称 1型神经纤维瘤抗体图片
英文名称 Anti-NF1/Neurofibromin 1
别 名 DKFZp686J1293; FLJ21220; Neurofibromatosis Noonan syndrome; Neurofibromatosis related protein NF 1; Neurofibromatosis related protein NF1; neurofibromatosis type I; Neurofibromatosis-related protein NF-1; Neurofibromin 1; Neurofibromin truncated; Neurofibromin1; NF 1; NF; NF1; NF1_HUMAN; NFNS; Type 1 Neurofibromatosis; von Recklinghausen disease neurofibromin; von Recklinghausen disease related protein VRNF; VRNF; WATS; Watson disease related protein WSS; Watson syndrome; WSS.
1型神经纤维瘤抗体图片是用于化学反应、分析化验、研究实验、教学实验、化学配方使用的纯净化学品，产品品质卓越，价格实惠，多种规格供应，售后完善。
浓 度 1mg/1ml
规 格 0.1ml/100μg 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse, Rabbit
产品类型 一抗
研究领域 肿瘤 细胞生物 免疫学 染色质和核信号 神经生物学 信号转导 表观遗传学 G蛋白信号
蛋白分子量 predicted molecular weight: 147/319kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Neurofibromin 1 C-terminus
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
1型神经纤维瘤抗体图片产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008].
Function : Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.DISEASE : Neurofibromatosis 1 (NF1) [MIM:162200]: A disease characterized by patches of skin pigmentation (cafe-au-lait spots), Lisch nodules of the iris, tumors in the peripheral nervous system and fibromatous skin tumors. Individuals with the disorder have increased susceptibility to the development of benign and malignant tumors. Note=The disease is caused by mutations affecting the gene represented in this entry.Leukemia, juvenile myelomonocytic (JMML) [MIM:607785]: An aggressive pediatric myelodysplastic syndrome/myeloproliferative disorder characterized by malignant transformation in the hematopoietic stem cell compartment with proliferation of differentiated progeny. Patients have splenomegaly, enlarged lymph nodes, rashes, and hemorrhages. Note=The disease is caused by mutations affecting the gene represented in this entry.Watson syndrome (WS) [MIM:193520]: A syndrome characterized by the presence of pulmonary stenosis, cafe-au-lait spots, and mental retardation. It is considered as an atypical form of neurofibromatosis. Note=The disease is caused by mutations affecting the gene represented in this entry.Familial spinal neurofibromatosis (FSNF) [MIM:162210]: Considered to be an alternative form of neurofibromatosis, showing multiple spinal tumors. Note=The disease is caused by mutations affecting the gene represented in this entry.Neurofibromatosis-Noonan syndrome (NFNS) [MIM:601321]: Characterized by manifestations of both NF1 and Noonan syndrome (NS). NS is a disorder characterized by dysmorphic facial features, short stature, hypertelorism, cardiac anomalies, deafness, motor delay, and a bleeding diathesis. Note=The disease is caused by mutations affecting the gene represented in this entry.Colorectal cancer (CRC) [MIM:114500]: A complex disease characterized by malignant lesions arising from the inner wall of the large intestine (the colon) and the rectum. Genetic alterations are often associated with progression from premalignant lesion (adenoma) to invasive adenocarcinoma. Risk factors for cancer of the colon and rectum include colon polyps, long-standing ulcerative colitis, and genetic family history. Note=The gene represented in this entry may be involved in disease pathogenesis.Similarity : Contains 1 CRAL-TRIO domain.Contains 1 Ras-GAP domain.Database links : UniProtKB/Swiss-Prot: P21359.2神经纤维素蛋白首先发现于神经细胞，是一种肿瘤抑制蛋白，通过调控Ras基因控制异常细胞生长，并且在cAMP信号传导通路中起调节作用.神经纤维瘤Ⅰ型(neurofibromatosis type 1,NF1)是一种由内分泌紊乱引起的神经纤维瘤,属于常染色体显性遗传病，其发病率为1/3500，主要表现为咖啡斑、神经纤维瘤、Lisch结节(虹膜错构瘤)等。每3，500个新生儿中就有一个是神经纤维细胞瘤I型患者，其临床表现为表皮或皮下多发性神经纤维瘤，良性多于恶性，常沿神经干分布。有时，神经纤维瘤会长大，或者发展到脑和脊髓，大约有一半以上患者智力低下。
1型神经纤维瘤抗体图片具有全、新、优、品、好四大特点：
全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。
新：产品更新速度较快，基本上每周都有新产品出现。
优：产品质量好，投诉比较少。
好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。
我们提供的标记服务，可根据您科研的需求，满足您的需要，质量保证，价格合理。
一、标记流程
委托标记服务，请下载并详细填写《委托标记申请单》，待我公司标记室技术人员研究、确认后答复，并办理委托标记事宜。
二、各种标记物制备的收费标准（RMB）
我们不但提供抗体和大分子蛋白的标记服务，还提供小分子多肽及小分子蛋白的各种标记服务，提供标记化合物的服务（此化合物必须适用于标记），价格另议。
一抗和二坑的区别：
第一抗体就是平常所说的抗体，即能和抗原特异性结合。
第二抗体是能和抗体结合的，即抗体的抗体。主要用于检测抗体的存在。
一抗是针对抗原的抗体，二抗是针对一抗的抗体。即抗体也可以充当抗原刺激机体产生抗体。也就是说，抗原进入机体刺激机体免疫系统产生免疫应答，由B细胞可以产生与相应抗原发生特异性结合的特殊蛋白质。
一抗二抗都是一种可以特异结合别的物质的基团，而且一抗可以至少结合两种其他基团（底物和二抗）。
一抗：可以特异结合底物，就是识别出我们想要检测的东西。一抗和底物结合与否用肉眼是看不出来的。
二抗：可以和一抗结合，并带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团），作用是检测一抗。 如果一抗自己带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团），则不需要二抗。但这样成本很高，因为一种一抗只识别一种底物。所以如今的设计一般是二抗带上可检测标记，再来检测一抗。而一抗识别底物。这样，当一抗结合到底物上，就可以通过二抗检测出来。
Immunoprecipitation/ IP Kit - Anti-ENO1 / Enolase 1 / alpha-enolase Immunomagnetic Beads IP 5 mL
Immunoprecipitation/ IP Kit - Anti-UCHL3 Immunomagnetic Beads IP 5 mL
Immunoprecipitation/ IP Kit - Anti-UCHL3 Immunomagnetic Beads IP 5 mL
Immunopre
CD146 / MCAM 抗體 (PE), 兔單抗 FCM IF ICC/IF 25 Test
IL-1RA / IL1RN 抗體 (FITC), 兔單抗 FCM 25 Test
CD146 / MCAM 抗體 (FITC), 兔單抗 FCM IF ICC/IF 25 Test
CD146 / MCAM 抗體 (APC), 鼠單抗 FCM 25 Test
CD146 / MCAM 抗體 (PE), 鼠單抗 FCM 25 Test
GAS2 抗體, 兔多抗, 抗原親和純化 WB 50 µg
FOS / c-Fos 抗體, 兔多抗, 抗原親和純化 IHC-P IF ICC/IF 50 µg
DPM1 抗體, 兔多抗, 抗原親和純化 IHC-P 50 µg
Cathepsin V / Cathepsin L2 / Preproprotein 抗體, 兔多抗, 抗原親和純化 ELISA WB 50 µg
GAPDH 抗體, 兔多抗, 抗原親和純化 ELISA WB IP 50 µg
用于样品稀释 PH7.0氯化钠-蛋白胨缓冲液瓶装颗粒培养基 250g
细菌生化鉴定 PH9.6肉汤 20支/盒
培养双歧杆菌用于乙酸和乳酸代谢产物测定 PYG液体培养基 250g
试剂A和试剂B各一支添加于100ml (027340)PYG液体培养基基础 PYG液体培养基冻干配套试剂 2种*5支/盒
试剂A和试剂B各一支添加于100ml (027340)PYG液体培养基基础 PYG液体培养基配套试剂 10支/盒
哥伦比亚CNA血琼脂 250g
改良胰蛋白胨大豆肉汤培养基（mTSB） 250g
萘啶酮酸2.25mg 2.25mg/支*5
金黄色葡萄球菌检验检验培养基
胰蛋白胨大豆肉汤 250g
1型神经纤维瘤抗体图片ELISA Kit for Human C-C motif chemokine 5 78-5000 pg/mL
人XXVII型胶原(COLXXVII)ELISA试剂盒 78-5000 pg/mL
ELISA Kit for Human Collagen alpha-1(XXVIII) chain 78-5000 pg/mL
人可溶性CD40配体(sCD40L)ELISA试剂盒 0.156-10 ng/mL
ELISA Kit for Human CD40 ligand 0.156-10 ng/mL
英文名称 Anti-NF1/Neurofibromin 1
别 名 DKFZp686J1293; FLJ21220; Neurofibromatosis Noonan syndrome; Neurofibromatosis related protein NF 1; Neurofibromatosis related protein NF1; neurofibromatosis type I; Neurofibromatosis-related protein NF-1; Neurofibromin 1; Neurofibromin truncated; Neurofibromin1; NF 1; NF; NF1; NF1_HUMAN; NFNS; Type 1 Neurofibromatosis; von Recklinghausen disease neurofibromin; von Recklinghausen disease related protein VRNF; VRNF; WATS; Watson disease related protein WSS; Watson syndrome; WSS.
1型神经纤维瘤抗体图片是用于化学反应、分析化验、研究实验、教学实验、化学配方使用的纯净化学品，产品品质卓越，价格实惠，多种规格供应，售后完善。
浓 度 1mg/1ml
规 格 0.1ml/100μg 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse, Rabbit
产品类型 一抗
研究领域 肿瘤 细胞生物 免疫学 染色质和核信号 神经生物学 信号转导 表观遗传学 G蛋白信号
蛋白分子量 predicted molecular weight: 147/319kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Neurofibromin 1 C-terminus
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
1型神经纤维瘤抗体图片产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008].
Function : Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.DISEASE : Neurofibromatosis 1 (NF1) [MIM:162200]: A disease characterized by patches of skin pigmentation (cafe-au-lait spots), Lisch nodules of the iris, tumors in the peripheral nervous system and fibromatous skin tumors. Individuals with the disorder have increased susceptibility to the development of benign and malignant tumors. Note=The disease is caused by mutations affecting the gene represented in this entry.Leukemia, juvenile myelomonocytic (JMML) [MIM:607785]: An aggressive pediatric myelodysplastic syndrome/myeloproliferative disorder characterized by malignant transformation in the hematopoietic stem cell compartment with proliferation of differentiated progeny. Patients have splenomegaly, enlarged lymph nodes, rashes, and hemorrhages. Note=The disease is caused by mutations affecting the gene represented in this entry.Watson syndrome (WS) [MIM:193520]: A syndrome characterized by the presence of pulmonary stenosis, cafe-au-lait spots, and mental retardation. It is considered as an atypical form of neurofibromatosis. Note=The disease is caused by mutations affecting the gene represented in this entry.Familial spinal neurofibromatosis (FSNF) [MIM:162210]: Considered to be an alternative form of neurofibromatosis, showing multiple spinal tumors. Note=The disease is caused by mutations affecting the gene represented in this entry.Neurofibromatosis-Noonan syndrome (NFNS) [MIM:601321]: Characterized by manifestations of both NF1 and Noonan syndrome (NS). NS is a disorder characterized by dysmorphic facial features, short stature, hypertelorism, cardiac anomalies, deafness, motor delay, and a bleeding diathesis. Note=The disease is caused by mutations affecting the gene represented in this entry.Colorectal cancer (CRC) [MIM:114500]: A complex disease characterized by malignant lesions arising from the inner wall of the large intestine (the colon) and the rectum. Genetic alterations are often associated with progression from premalignant lesion (adenoma) to invasive adenocarcinoma. Risk factors for cancer of the colon and rectum include colon polyps, long-standing ulcerative colitis, and genetic family history. Note=The gene represented in this entry may be involved in disease pathogenesis.Similarity : Contains 1 CRAL-TRIO domain.Contains 1 Ras-GAP domain.Database links : UniProtKB/Swiss-Prot: P21359.2神经纤维素蛋白首先发现于神经细胞，是一种肿瘤抑制蛋白，通过调控Ras基因控制异常细胞生长，并且在cAMP信号传导通路中起调节作用.神经纤维瘤Ⅰ型(neurofibromatosis type 1,NF1)是一种由内分泌紊乱引起的神经纤维瘤,属于常染色体显性遗传病，其发病率为1/3500，主要表现为咖啡斑、神经纤维瘤、Lisch结节(虹膜错构瘤)等。每3，500个新生儿中就有一个是神经纤维细胞瘤I型患者，其临床表现为表皮或皮下多发性神经纤维瘤，良性多于恶性，常沿神经干分布。有时，神经纤维瘤会长大，或者发展到脑和脊髓，大约有一半以上患者智力低下。
1型神经纤维瘤抗体图片具有全、新、优、品、好四大特点：
全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。
新：产品更新速度较快，基本上每周都有新产品出现。
优：产品质量好，投诉比较少。
好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。
我们提供的标记服务，可根据您科研的需求，满足您的需要，质量保证，价格合理。
一、标记流程
委托标记服务，请下载并详细填写《委托标记申请单》，待我公司标记室技术人员研究、确认后答复，并办理委托标记事宜。
二、各种标记物制备的收费标准（RMB）
我们不但提供抗体和大分子蛋白的标记服务，还提供小分子多肽及小分子蛋白的各种标记服务，提供标记化合物的服务（此化合物必须适用于标记），价格另议。
一抗和二坑的区别：
第一抗体就是平常所说的抗体，即能和抗原特异性结合。
第二抗体是能和抗体结合的，即抗体的抗体。主要用于检测抗体的存在。
一抗是针对抗原的抗体，二抗是针对一抗的抗体。即抗体也可以充当抗原刺激机体产生抗体。也就是说，抗原进入机体刺激机体免疫系统产生免疫应答，由B细胞可以产生与相应抗原发生特异性结合的特殊蛋白质。
一抗二抗都是一种可以特异结合别的物质的基团，而且一抗可以至少结合两种其他基团（底物和二抗）。
一抗：可以特异结合底物，就是识别出我们想要检测的东西。一抗和底物结合与否用肉眼是看不出来的。
二抗：可以和一抗结合，并带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团），作用是检测一抗。 如果一抗自己带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团），则不需要二抗。但这样成本很高，因为一种一抗只识别一种底物。所以如今的设计一般是二抗带上可检测标记，再来检测一抗。而一抗识别底物。这样，当一抗结合到底物上，就可以通过二抗检测出来。
Immunoprecipitation/ IP Kit - Anti-ENO1 / Enolase 1 / alpha-enolase Immunomagnetic Beads IP 5 mL
Immunoprecipitation/ IP Kit - Anti-UCHL3 Immunomagnetic Beads IP 5 mL
Immunoprecipitation/ IP Kit - Anti-UCHL3 Immunomagnetic Beads IP 5 mL
Immunopre
CD146 / MCAM 抗體 (PE), 兔單抗 FCM IF ICC/IF 25 Test
IL-1RA / IL1RN 抗體 (FITC), 兔單抗 FCM 25 Test
CD146 / MCAM 抗體 (FITC), 兔單抗 FCM IF ICC/IF 25 Test
CD146 / MCAM 抗體 (APC), 鼠單抗 FCM 25 Test
CD146 / MCAM 抗體 (PE), 鼠單抗 FCM 25 Test
GAS2 抗體, 兔多抗, 抗原親和純化 WB 50 µg
FOS / c-Fos 抗體, 兔多抗, 抗原親和純化 IHC-P IF ICC/IF 50 µg
DPM1 抗體, 兔多抗, 抗原親和純化 IHC-P 50 µg
Cathepsin V / Cathepsin L2 / Preproprotein 抗體, 兔多抗, 抗原親和純化 ELISA WB 50 µg
GAPDH 抗體, 兔多抗, 抗原親和純化 ELISA WB IP 50 µg
用于样品稀释 PH7.0氯化钠-蛋白胨缓冲液瓶装颗粒培养基 250g
细菌生化鉴定 PH9.6肉汤 20支/盒
培养双歧杆菌用于乙酸和乳酸代谢产物测定 PYG液体培养基 250g
试剂A和试剂B各一支添加于100ml (027340)PYG液体培养基基础 PYG液体培养基冻干配套试剂 2种*5支/盒
试剂A和试剂B各一支添加于100ml (027340)PYG液体培养基基础 PYG液体培养基配套试剂 10支/盒
哥伦比亚CNA血琼脂 250g
改良胰蛋白胨大豆肉汤培养基（mTSB） 250g
萘啶酮酸2.25mg 2.25mg/支*5
金黄色葡萄球菌检验检验培养基
胰蛋白胨大豆肉汤 250g
1型神经纤维瘤抗体图片ELISA Kit for Human C-C motif chemokine 5 78-5000 pg/mL
人XXVII型胶原(COLXXVII)ELISA试剂盒 78-5000 pg/mL
ELISA Kit for Human Collagen alpha-1(XXVIII) chain 78-5000 pg/mL
人可溶性CD40配体(sCD40L)ELISA试剂盒 0.156-10 ng/mL
ELISA Kit for Human CD40 ligand 0.156-10 ng/mL
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1型神经纤维瘤抗体图片
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