- ￥2570
- peprotech
- 400-21
- peprotech
- 2025年10月25日
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- 详细信息
- 技术资料
- 供应商：
上海研卉生物科技有限公司
- 库存：
400-21
- 英文名：
Recombinant Rat Leptin
- 规格：
1mg
Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant Rat Leptin is a 16.2 kDa protein containing 147 amino acid residues.
Source: E.coli
Synonyms: Obesity protein (OB)
AA Sequence: MVPIHKVQDD TKTLIKTIVT RINDISHTQS VSARQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQILTSLP SQNVLQIAHD LENLRDLLHL LAFSKSCSLP QTRGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDLSPEC
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by an in vivo assay using the ob/ob mouse obesity model and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5µg leptin/gm of body weight for 7 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed compared to saline-treated controls.
Calculated Molecular Weight: 16.2 kDa
Accession Number: P50596
Gene ID: 25608
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