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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
基质金属蛋白酶20抗体
- 宿主:
Rabbit
- 供应商:
上海研卉生物科技有限公司
- 抗原来源:
Goat,Rabbit,Mouse
- 保质期:
一年
- 保存条件:
低温
- 适应物种:
Human
- 应用范围:
WB/ELISA
- 库存:
大量
- 抗体英文名:
Anti-MMP20
- 是否单克隆:
多克隆
- 规格:
50ul
名 称:
MMP20 抗体
货 号:
DF7694
来 源:
Rabbit
应 用:
WB,ELISA
反 应:
Human
预 测:
Bovine(91%), Horse(100%), Sheep(91%), Rabbit(100%), Dog(82%), Xenopus(80%)
蛋白号:
O60882
分子量:
54 kDa
浓 度:
1mg/ml
Alternative Names:Expand▼
AI2A2; Enamel metalloproteinase; Enamelysin; Matrix metalloproteinase 20; Matrix metalloproteinase-20; MMP 20; MMP-20; MMP20; MMP20_HUMAN;
Applications:
WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Reactivity:
Human
Predicted Reactivity:
Bovine(91%), Horse(100%), Sheep(91%), Rabbit(100%), Dog(82%), Xenopus(80%)
Source:
Rabbit
Clonality:
Polyclonal
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Specificity:
MMP20 Antibody detects endogenous levels of total MMP20.
Format:
Liquid
Concentration:
1mg/ml
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文献和实验【摘要】目的探讨嵌合抗CD20抗体Fab’片段的抗肿瘤机制。方法应用MTT法检测Fab’片段对Raji细胞生长的抑制作用,用Annexin V-FITC和PI测定Fab’片段对Raji细胞凋亡的诱导作用,用RT-PCR和Western blot检测Raji细胞中bcl-2表达的变化。结果嵌合抗CD20Fab’片段对Raji细胞具有明显的抑制作用IC50值为24.2 µg/ml,并呈剂量依赖性;嵌合抗CD20Fab’片段能诱导Raji细胞的凋亡,并降低Raji细胞中bcl-2基因及其蛋白的表达
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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