- ¥2996
- cst
- 9027
- USA
- 2025年07月15日
- IHC
- Goat，Rabbit，Mouse
- 人
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- 详细信息
- 询价记录
- 技术资料
- 抗体名：
Ki-67
- 抗体英文名：
Anti-Ki-67（mo monoclonal）
- 应用范围：
IHC
- 宿主：
Goat，Rabbit，Mouse
- 保质期：
一年
- 适应物种：
人
- 供应商：
上海研卉生物科技有限公司
- 是否单克隆：
单克隆
- 保存条件：
低温
- 规格：
0.1ml
Ki-67 (D2H10) Rabbit mAb (IHC Specific) #9027
Immunohistochemistry (Paraffin)A. Solutions and Reagents
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalent grade water.
Xylene.
Ethanol, anhydrous denatured, histological grade (100% and 95%).
Deionized water (dH2O).
Hematoxylin (optional).
Wash Buffer:
Immunohistochemistry 1:400
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity / Sensitivity
Ki-67 (D2H10) Rabbit mAb (IHC Specific) recognizes endogenous levels of total Ki-67 protein.
Species Reactivity: Human
Background
Ki-67, named after the location where it was discovered (Kiel University, Germany), is a nuclear nonhistone protein (1) that is universally expressed among proliferating cells and absent in quiescent cells (2). Ki-67 detects proliferating cells in G1, S, G2, and mitosis, but not in the G0 resting phase. Research studies have shown that high levels of Ki-67 are associated with poorer breast cancer survival (3). Research studies have explored the use of Ki-67, along with other markers, as potential prognostic or predictive markers in breast cancer and other malignant diseases (4).
1. Gerdes, J. et al. (1983) Int J Cancer 31, 13-20.
2. Weigel, M.T. and Dowsett, M. (2010) Endocr Relat Cancer 17, R245-62.
3. Jones, R.L. et al. (2009) Breast Cancer Res Treat 116, 53-68.
4. Yerushalmi, R. et al. (2010) Lancet Oncol 11, 174-83.
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