- ¥2996
- cst
- 9027
- USA
- 2025年07月15日
- IHC
- Goat，Rabbit，Mouse
- 人
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 抗体名：
Ki-67
- 抗体英文名：
Anti-Ki-67（mo monoclonal）
- 应用范围：
IHC
- 宿主：
Goat，Rabbit，Mouse
- 保质期：
一年
- 适应物种：
人
- 供应商：
上海研卉生物科技有限公司
- 是否单克隆：
单克隆
- 保存条件：
低温
- 规格：
0.1ml
Ki-67 (D2H10) Rabbit mAb (IHC Specific) #9027
Immunohistochemistry (Paraffin)A. Solutions and Reagents
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalent grade water.
Xylene.
Ethanol, anhydrous denatured, histological grade (100% and 95%).
Deionized water (dH2O).
Hematoxylin (optional).
Wash Buffer:
Immunohistochemistry 1:400
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity / Sensitivity
Ki-67 (D2H10) Rabbit mAb (IHC Specific) recognizes endogenous levels of total Ki-67 protein.
Species Reactivity: Human
Background
Ki-67, named after the location where it was discovered (Kiel University, Germany), is a nuclear nonhistone protein (1) that is universally expressed among proliferating cells and absent in quiescent cells (2). Ki-67 detects proliferating cells in G1, S, G2, and mitosis, but not in the G0 resting phase. Research studies have shown that high levels of Ki-67 are associated with poorer breast cancer survival (3). Research studies have explored the use of Ki-67, along with other markers, as potential prognostic or predictive markers in breast cancer and other malignant diseases (4).
1. Gerdes, J. et al. (1983) Int J Cancer 31, 13-20.
2. Weigel, M.T. and Dowsett, M. (2010) Endocr Relat Cancer 17, R245-62.
3. Jones, R.L. et al. (2009) Breast Cancer Res Treat 116, 53-68.
4. Yerushalmi, R. et al. (2010) Lancet Oncol 11, 174-83.
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- 作者
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- 询问日期
文献和实验baibai17 今天开题，导师问了个问题：ki67为什么叫ki67？当场傻住······恳请各位老师指教！谢谢。 keavin521 The Ki-67 protein was originally defined by the prototype monoclonal antibody Ki-67 (Gerdes et al., 1983),which was generated by immunizing mice
Flow Cytometric Detection of Proliferation-Associated Antigens, PCNA and Ki-67
The rapid evolution of monoclonal antibody (MAb) technology has resulted in an ever-growing repertoire of proteins becoming accessible for study using immunohistochemical techniques. Nuclear antigens represent a class of proteins
Immunohistochemistry of p53, Bcl-2, and Ki-67 as Predictors of Chemosensitivity
Chemosensitivity is affected by molecular biological factors, including factors related to the induction of apoptosis and the activity of proliferation. We analyzed immunohistochemically the expression of p53, Bcl-2, and Ki-67 in various
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