重组人巨噬细胞迁移抑制因子(MIF)

特别提示：包括重组人巨噬细胞迁移抑制因子(MIF)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人巨噬细胞迁移抑制因子(MIF)
英文名称：Recombinant Human Macrophage migration inhibitory factor
产品货号：JN1188
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Ala115表达纯化得来。

MIF质量控制：＞95%(还原性SDS-PAGE)

MIF制剂：液体

MIF保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于MIF：
Human MIF is a 12.5 kDa, 115 amino acid (aa) nonglycosylated polypeptide that is synthesized without asignal sequence .Secretion occurs nonclassically via an ABCA1 transporter.Pro-inflammatory cytokine.Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites ofinflammation suggests a role as mediator in regulating the function of acrophages in host defense.Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase anddopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clearwhether the tautomerase activity has any physiological relevance, and whether it is important for cytokineactivity.

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