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- 文献和实验
- 技术资料
- 供应商：
安诺伦（北京）生物科技有限公司
- 规格：
50 ug
研究领域：Cancer, Neurobiology,
存储温度：Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
靶点/蛋白质：Full-length recombinant human ASH2L was expressed in E. coli cells using an N-terminal GST tag.
来源：E.coli
存储溶液：50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
参考文献：1. Patel A, et al: On the mechanism of multiple lysine methyla-tion by the human mixed lineage leukemia protein-1 (MLL1) core complex. J Biol Chem. 2009 284(36):24242-56. 2. Qi J, et al: Absent, small or homeotic 2-like protein (ASH2L) enhances the transcription of the estrogen receptor α gene through GATA-binding protein 3 (GATA3). J Biol Chem. 2014 289(45):31373-81.
别名：ASH2L2
应用：Methyltransferase Assay
官网链接：https://www.signalchem.com/product_details.php?id=12728
商品关键词：ASH2L Protein,A372-30BG-20,SignalChem
简单描述：Full-length recombinant human ASH2L was expressed in E. coli cells using an N-terminal GST tag.
Species: Human
Tag: GST tag
Sequence: Full length
Genbank Number: BC015882
Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Molecular Weight: ~130 kDa
官网链接: www.annoron.com
办公电话: 010-56256916
官方售后: 400-965-8633
企业QQ: 3198592576、3212875861
存储温度：Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
靶点/蛋白质：Full-length recombinant human ASH2L was expressed in E. coli cells using an N-terminal GST tag.
来源：E.coli
存储溶液：50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
参考文献：1. Patel A, et al: On the mechanism of multiple lysine methyla-tion by the human mixed lineage leukemia protein-1 (MLL1) core complex. J Biol Chem. 2009 284(36):24242-56. 2. Qi J, et al: Absent, small or homeotic 2-like protein (ASH2L) enhances the transcription of the estrogen receptor α gene through GATA-binding protein 3 (GATA3). J Biol Chem. 2014 289(45):31373-81.
别名：ASH2L2
应用：Methyltransferase Assay
官网链接：https://www.signalchem.com/product_details.php?id=12728
商品关键词：ASH2L Protein,A372-30BG-20,SignalChem
简单描述：Full-length recombinant human ASH2L was expressed in E. coli cells using an N-terminal GST tag.
Species: Human
Tag: GST tag
Sequence: Full length
Genbank Number: BC015882
Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Molecular Weight: ~130 kDa
官网链接: www.annoron.com
办公电话: 010-56256916
官方售后: 400-965-8633
企业QQ: 3198592576、3212875861
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文献和实验相关实验
Tau 蛋白是一种微管相关蛋白，分子量 50～75 kDa，主要位于神经元轴突中，是维持骨骼神经元系统稳定性所需的重要分子。
PKA系统(protein kinase A system, PKA)
是G蛋白偶联系统的一种信号转导途径。信号分子作用于膜受体后，通过G蛋白激活腺苷酸环化酶, 产生第二信使cAMP后,激活蛋白激酶A进行信号的放大。故将此途径称为PKA信号转导系统。如胰高血糖素和肾上腺素都是很小的水溶性的胺,它们在结构上没有相同之处,并作用于不同的膜受体, 但都能通过G蛋白激活腺苷酸环化酶, 最后通过蛋白激酶A进行信号放大。
Tau pathology refers to molecular mechanisms leading to the intracellular aggregation of abnormally modified Tau protein isoforms and to the propagation of this degenerating process along neuronal �circuitry. Tau proteins belong to the family
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Tau-441, PKA-phosphorylated
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