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p16INK4A Protein

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  • ¥4462.50
  • SignalChem
  • 加拿大
  • 2025年07月13日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      安诺伦(北京)生物科技有限公司

    • 规格

      20 ug

    研究领域:Cancer, Neurobiology,

    存储温度:Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

    靶点/蛋白质:Full-length recombinant human ASH2L was expressed in E. coli cells using an N-terminal GST tag.

    来源:E.coli

    存储溶液:50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

    参考文献:1. Patel A, et al: On the mechanism of multiple lysine methyla-tion by the human mixed lineage leukemia protein-1 (MLL1) core complex. J Biol Chem. 2009 284(36):24242-56. 2. Qi J, et al: Absent, small or homeotic 2-like protein (ASH2L) enhances the transcription of the estrogen receptor α gene through GATA-binding protein 3 (GATA3). J Biol Chem. 2014 289(45):31373-81.

    别名:ASH2L2

    应用:Methyltransferase Assay

    官网链接:https://www.signalchem.com/product_details.php?id=12728

    商品关键词:ASH2L Protein,A372-30BG-20,SignalChem

    简单描述:Full-length recombinant human ASH2L was expressed in E. coli cells using an N-terminal GST tag.

    Species: Human

    Tag: GST tag

    Sequence: Full length

    Genbank Number: BC015882

    Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet. 

    Molecular Weight: ~130 kDa 


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    图标文献和实验
    相关实验
    • p16INK4A and Familial Melanoma

      . This phase is controlled by several protein complexes including those consisting of cyclin-dependent kinases (CDK4 and CDK6) and cyclin D. These complexes are inhibited by the INK4 family of proteins—p16INK4A , p15INK4B , p18INK4C , and p19INK4D . Genetic

    • Analysis of p16INK4a and Integrated HPV Genomes as Progression Markers

      that never develop a lesion. Only a small percentage of low-grade dysplasias finally grow out to invasive cancer. Several biomarkers can be used to identify lesions at risk for malignant progression. Overexpression of p16INK4a is induced by the viral oncoprotein E7

    • Sensitive Detection of Hypermethylated p16INK4a Alleles in Exfoliative Tissue Material

      Epigenetic DNA modification by aberrant methylation of cytosine residues is thought to be an important mechanism contributing to tumorigenesis. Methylation of cytosines normally occurs at distinct sites of the genome containing stretches

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