The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
克隆性:
多克隆
供应商:
安诺伦(北京)生物科技有限公司
应用范围:
FC, FA, IHC, IP
规格:
100 μg
研究领域:Innate Immunity
来源:Rat IgG2b, kappa
存储溶液:Phosphate-buffered aqueous solution, ph7.2.
参考文献:Fleming, T. J., Fleming, M. L., & Malek, T. R. (1993). Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family.The Journal of Immunology, 151(5), 2399-2408.Hestdal, K., Ruscetti, F. W., Ihle, J. N., Jacobsen, S. E., Dubois, C. M., Kopp, W. C., ... & Keller, J. R. (1991). Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells. The Journal of Immunology,147(1), 22-28.Huang, B., Zhao, J., Shen, S., Li, H., He, K. L., Shen, G. X., ... & Feng, Z. H. (2007). Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling. Cancer Research, 67(9), 4346-4352.
简单描述:The RB6-8C5 monoclonal antibody reacts with the mouse Ly-6G (also known as Gr-1). The Ly-6G protein is a myeloid differentiation antigen of 21-25 kDa, expressed in a regulated manner by the myeloid lineage in the bone marrow, where the level of antigen expression is correlated with the granulocyte maturation and differentiation. In the bone marrow, the antigen is not expressed by the erythroid cells.From the peripheric cells, RB6-8C5 binds with monocytes, neutrophils and eosinophils.As a marker for the mouse monocytes, macrophages and granulocytes, the RB6-8C5 antibody is usually combined with M1/70, a macrophage labeling antibody (Anti-CD11b), for phenotypic analysis.