Recombinant full-length human protein was used as the immunogen for the recombinant Histone H1 antibody.
亚型:
Rabbit IgG, kappa
克隆性:
单克隆
适应物种:
Human. Other species not tested.
宿主:
Rabbit
规格:
7 ml
产品类型:
Primary antibody
纯化方法:
Purified
通用信息:
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
产品描述:
Five major families of histones exist: H1/H5, H2A, H2B, H3, and H4. Histones H2A, H2B, H3 and H4 are known as the core histones, while histones H1/H5 are known as the linker histones. The core histones all exist as dimers, which are similar in that they all possess the histone fold domain; three alpha helices linked by two loops. It is this helical structure that allows for interaction between distinct dimers, particularly in a head-tail fashion (also called the handshake motif). The linker histone H1 binds the nucleosome at the entry and exit sites of the DNA, thus locking the DNA into place and allowing the formation of higher order structure. [Wiki]
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