- ￥3320
- Biogems
- AF-214-14-20µg
- 美国
- 2025年07月12日
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20µg
靶点/蛋白质：MHIHGCDKN HLREIIGIL NEVTGEGTP CTEMDVPNV LTATKNTTE SELVCRASK VLRIFYLKH GKTPCLKKN SSVLMELQR LFRAFRCLD SSISCTMNE SKSTSLKDF LESLKSIMQ MDYS
特异性：Rat, Pig Intestinal Worm
官网链接：http://www.bio-gems.com/recombinant-proteins/animal-free-cytokines/animal-free-recombinant-murine-il-4.html
商品关键词：Animal-Free Recombinant Murine IL-4,AF-214-14-20µg ,Biogems
简单描述：IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 121 amino acid residues. Manufactured using all non-animal reagents.
Purity: Above 98% as determined by SDS-PAGE Analysis.
Biological Activity: The ED50 was determined by the dose-dependent proliferation of murine HT-2 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg.
Cell Type: T Cells
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文献和实验Experimental animal models are available for the development of new treatment. Murine animal models have particular advantages for comparative study to evaluate the efficacy and safety of different treatment modalities because many mice
Production and Characterization of Recombinant Human and Murine TNF
assays using murine L-M cells. Purified hTNF and mTNF can be used for in vitro and in vivo studies in animal models.
Recombinant Immunotoxins with Low Endotoxins for Clinical and Animal Studies
Recombinant immunotoxin (RIT) contains the Fv portion of the antibody fused to the truncated form of toxin and are ongoing in clinical trials for cancer therapy. To obtain high yields of products, RITs are produced in Escherichia coli (E
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