- ￥18529
- Biogems
- AF-315-05-1mg
- 美国
- 2025年07月09日
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1mg
靶点/蛋白质：MHGTVIESL ESLNNYFNS SGIDVEEKS LFLDIWRNW QKDGDMKIL QSQIISFYL RLFEVLKDN QAISNNISV IESHLITTF FSNSKAKKD AFMSIAKFE VNNPQVQRQ AFNELIRVV HQLLPESSL RKRKRSRC
特异性：Rabbit, Rat
官网链接：http://www.bio-gems.com/recombinant-proteins/animal-free-cytokines/animal-free-recombinant-murine-ifn.html
商品关键词：Animal-Free Recombinant Murine IFN-γ,AF-315-05-1mg,Biogems
简单描述：IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues. Manufactured using all non-animal reagents.
Purity: Above 98% as determined by SDS-PAGE Analysis.
Biological Activity: Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
Cell Type: B Cells, Monocytes and Macrophages, NK and NKT Cells
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文献和实验Experimental animal models are available for the development of new treatment. Murine animal models have particular advantages for comparative study to evaluate the efficacy and safety of different treatment modalities because many mice
Production and Characterization of Recombinant Human and Murine TNF
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Recombinant Immunotoxins with Low Endotoxins for Clinical and Animal Studies
Recombinant immunotoxin (RIT) contains the Fv portion of the antibody fused to the truncated form of toxin and are ongoing in clinical trials for cancer therapy. To obtain high yields of products, RITs are produced in Escherichia coli (E
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