简单描述:G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant murine G-CSF is a 19.0 kDa protein consisting of 179 amino acid residues. Manufactured using all non-animal reagents.
Purity: Above 98% as determined by SDS-PAGE Analysis.
Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.05 ng/ml, corresponding to a s
Cell Type: Monocytes and Macrophages, Stem Cells, Endothelial Cells