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- Biogems
- AF-200-01RA-100µg
- 美国
- 2025年07月13日
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100µg
靶点/蛋白质：MRPSGRKSS KMQAFRIWD VNQKTFYLR NNQLVAGYL QGPNVNLEE KIDVVPIEP HALFLGIHG GKMCLSCVK SGDETRLQL EAVNITDLS ENRKQDKRF AFIRSDSGP TTSFESAAC PGWFLCTAM EADQPVSLT NMPDEGVMV TKFYFQEDE
特异性：Frog, Mouse, Rat
官网链接：http://www.bio-gems.com/recombinant-proteins/animal-free-cytokines/animal-free-recombinant-human-il-1ra.html
商品关键词：Animal-Free Recombinant Human IL-1Ra,AF-200-01RA-100µg ,Biogems
简单描述：Interleukin-1 receptor antagonist (IL-1RA) is a naturally occurring inflammatory inhibitor protein. It inhibits the activity of IL-1α and IL-1β by competitively blocking binding to their type I and type II receptors. IL-1Ra is produced by corneal epithelial cells, monocytes, neutrophils, macrophages, and fibroblasts. Therapeutically, IL-1Ra may help in the treatment of sepsis, cachexia, rheumatoid arthritis, chronic myelogenous leukemia, asthma, psoriasis, and inflammatory bowel disease. Recombinant human IL-1Ra is a 17.2 kDa protein consisting of 153 amino acid residues. Manufactured using all non-animal reagents.
Purity: Above 124% as determined by SDS-PAGE Analysis.
Biological Activity: Determined by its ability to inhibit the IL-1α stimulation of murine D10S cell. The expected ED50 is 20-40 ng/ml in the presence of 50 pg/ml of IL-1α.
Cell Type: Monocytes and Macrophages
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