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- 规格:
25µg
靶点/蛋白质:MIVKAGITI PRNPGCPNS EDKNFPRTV MVNLNIHNR NTNTNPKRS SDYYNRSTS PWNLHRNED PERYPSVIW EAKCRHLGC INADGNVDY HMNSVPIQQ EILVLRREP PHCPNSFRL EKILVSVGC TCVTPIVHH VA
特异性:Mouse
官网链接:http://www.bio-gems.com/recombinant-proteins/animal-free-cytokines/animal-free-recombinant-human-il-17-il-17a.html
商品关键词:Animal-Free Recombinant Human IL-17 (IL-17A),AF-200-17-25µg ,Biogems
简单描述:The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant human IL-17A is a 31.3 kDa disulfide-linked homodimer of two 137 amino acid polypeptide chains. Manufactured using all non-animal reagents.
Purity: Above 122% as determined by SDS-PAGE Analysis.
Biological Activity: Assay #1: The ED50 as determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblasts was found to be approximately 2 ng/ml. Assay #2: Measured by its ability to
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文献和实验Human IL-2 Enzyme Immunoassay (EIA)
Increased division and maturation of activated helper T cells Stimulation of neutrophils Stimulus for the secretion of interferon-( and tumor necrosis factors - aphla and - Beta from peripheral mononuclear cells. The Endogen Human IL-
Culturing Human Embryonic Stem Cells in Feeder-Free Conditions
Culturing Human Embryonic Stem Cells in Feeder-Free Conditions Sohyun L. McElroy1 and Renee A. Reijo Pera Center for Human Embryonic Stem Cell Research and Education, Institute for Stem Cell Biology and Regenerative Medicine
Evaluation of IL-2-Withdrawal-Induced Apoptosis in Human T Lymphocytes
pathway of lymphocyte apoptosis triggered by starvation for IL-2 or other survival cytokines.
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