- ¥1380 - 2200
- LMAI Bio
- LM-5721R
- 进口/国产
- 2025年11月07日
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
- Rabbit
- Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海联迈生物工程有限公司
- 库存：
大量
- 目录编号：
LM-5721R
- 克隆性：
多克隆
- 抗原来源：
Rabbit
- 保质期：
1年
- 抗体英文名：
MBNL3
- 抗体名：
毒蕈碱样蛋白3抗体
- 宿主：
Rabbit
- 适应物种：
Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
- 免疫原：
KLH conjugated synthetic peptide derived from human MBNL3:251-354/354
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
- 浓度：
1mg/ml
- 保存条件：
Store at -20 °C
- 规格：
100ul 200ul
| 英文名称 | MBNL3 |
| 中文名称 | 毒蕈碱样蛋白3抗体 |
| 别 名 | MBLX; CHCR; Cys3His CCG1 required protein; MBLX39; MBNL 3; MBXL; Muscleblind like protein 3; Muscleblind like X linked protein; Protein HCHCR; MBNL3_HUMAN. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 染色质和核信号 细胞周期蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Sheep, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 39kDa |
| 细胞定位 | 细胞核 细胞浆 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MBNL3:251-354/354 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: MBNL3 has been shown to inhibit muscle differentiation. MBNL3 belongs to a highly conserved family of tissue-specific alternative splicing regulators. This family is known to regulate terminal muscle differentiation through alternative splicing control and several groups have suggested that the family participates in the differentiation of photoreceptors, neurons, adipocytes and blood cell types. MBNL3 is expressed in myoblasts, muscle precursor cells, and during the early stages of myogenesis, but is detected at very low levels in terminally differentiated myotubes. MBNL proteins have been shown to sequester foci of expanded-repeat transcripts and are thought to therefore play a role in the molecular pathology of a group of neuromuscular diseases including the Myotonic Dystrophies. Function: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction. Subcellular Location: Nucleus. Cytoplasm. Note=Greater concentration in the nucleus. In both DM1 and DM2 patients, colocalizes with nuclear foci of retained expanded-repeat transcripts. Tissue Specificity: Highly expressed in the placenta. Similarity: Belongs to the muscleblind family. Contains 4 C3H1-type zinc fingers. SWISS: Q9NUK0 Gene ID: 55796 Database links: Entrez Gene: 55796 Human Entrez Gene: 171170 Mouse Entrez Gene: 302492 Rat Omim: 300413 Human SwissProt: Q9NUK0 Human SwissProt: Q8R003 Mouse Unigene: 105134 Human Unigene: 596347 Human Unigene: 295324 Mouse Unigene: 105030 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 |  Paraformaldehyde-fixed, paraffin embedded (Mouse placenta); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MBNL3) Polyclonal Antibody, Unconjugated (bs-5721R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining. |
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文献和实验试剂和材料：1. 一抗：（1） ABCG2-----------------小鼠单克隆BXP-21---------1：100（2） 连接蛋白-43-----------兔多克隆CX43-------------1：100（3） 细胞角蛋白3（K3）-----小鼠单克隆AE5----------- 1：500（4） 细胞角蛋白12（K12）---兔多克隆J7-------------- 1：2002. 二抗；（1） 抗小鼠IgG-------------Alexa-488----
人血管生成素样蛋白3(ANGPTL3)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人血管生成素样蛋白3 (ANGPTL3)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 ANGPTL3 单抗包被于酶标板上，标准品和样品中的 ANGPTL3与单抗结合，加入生物素化的抗人
网络 第二节 免疫铁蛋白技术 一、基本原理 铁蛋白是一种含铁约占23%的蛋白质，分子量460kD,直径10～12μm。抗体与铁蛋白通过低分子量的双功能 试剂 结合为一种双分子复合物。此复合物既保留抗体的免疫活性，同时因为铁蛋白含有致密的铁离子核心，铁胶粒直径核心为55～60nm含2000～3000个铁原子
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