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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥539.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥222.0 |
| 规格: | 5 mg | 产品价格: | ¥490.0 |
| 规格: | 10 mg | 产品价格: | ¥760.0 |
| 规格: | 25 mg | 产品价格: | ¥1406.0 |
| 规格: | 50 mg | 产品价格: | ¥2109.0 |
| 规格: | 100 mg | 产品价格: | ¥3058.0 |
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NIH-12848
CAS No. : 959551-10-1
MCE 国际站:NIH-12848
产品活性:NIH-12848 是推定的磷脂酰肌醇 5-磷酸4-激酶 γ (PI5P4Kγ) 抑制剂,IC50 值为 1 μM。
研究领域:Others
作用靶点:Others
In Vitro: NIH-12848 inhibits PI5P4Kγ with an IC50 of approximately 1 μM but does not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. NIH-12848 inhibits the translocation of Na+/ K+-ATPase to the plasma membrane that occurs when mpkCCD cells grow to confluence and also prevents reversibly their forming of ‘domes’ on the culture dish. Both these NIH-12848-induced effects are mimicked by specific RNAi knockdown of PI5P4Kγ, but not that of PI5P4Ks α or β. NIH-12848 could be a potentially powerful tool for exploring the cell physiology of PI5P4Ks.
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文献和实验A safe method of extracting DNA from Coccidioides immitis
. Acknowledgements: Norman Pace suggested the lysis buffer recipe and the use of Proteinase K. Financial support came from NIH-NIAID grant AI28545. Figure 1. Genomic DNA extracted from 10 mg lyophilized C. immitis after killing with steam. a, b
意思,发错了,是913777151@qq.com 已发 小小小白兔 看到一篇文献综述,不知对你有帮助没?p53-Mdm2 inhibitors: patent review (2009 - 2010) http://www.ncbi.nlm.nih.gov/pubmed/22316395 http://informahealthcare.com/doi/abs/10.1517/13543776.2012.656593
首先打开NCBI主页,大E浏览器有时候打不开,可以换个浏览器试试http://www.ncbi.nlm.nih.gov/然后按照以下步骤进行就可以了打开主页后,选择Gene,然后在后面输入目的基因名,基因后面可以加空格然后加种属缩写,不知道种属缩写也可以不加点击Search找到目的基因,注意后面标记的种属,然后点基因名进入下一页面后,向下拉,直到mRNA and Protein,点击红色数字向下拉复制序列,然后另打开NCBI主页,点右侧第五个Blast向下翻到specialized blast
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