- ¥160 - 2440
- 百奥莱博
- YT750-MPZ
- 北京
- 2025年07月12日
- WB,FC, IHC,ICC, IF
- 兔
- 人，小鼠，大鼠
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
北京百奥莱博科技有限公司
- 库存：
865
- 级别：
多克隆抗体
- 目录编号：
YT750
- 克隆性：
多克隆
- 保质期：
二年
- 抗体英文名：
p70 S6 Kinase β Rabbit Polyclonal Antibody
- 抗体名：
兔抗p70 S6 Kinase β多克隆抗体抗体
- 宿主：
兔
- 适应物种：
人，小鼠，大鼠
- 形态：
液体
- 应用范围：
WB,FC, IHC,ICC, IF
- 浓度：
1mg/ml
- 保存条件：
-20℃冻存，避光
特别提示：包括兔抗p70 S6 Kinase β抗体在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
产品名称：兔抗p70 S6 Kinase β抗体
英文名称：p70 S6 Kinase β Rabbit Polyclonal Antibody
产品规格：50μl
本品为来源于兔的抗p70 S6 Kinase β的多克隆抗体。
宿主：兔
克隆性：多克隆抗体
用途：WB,FC, IHC,ICC, IF
交叉反应性：人，小鼠，大鼠
分子量：70KDa
推荐稀释比例：WB(1:500-1:1000),IF(1:200),IHC(1:200),ICC(1:200),FC(1:100-1:200)
| About this Antibody | |
| Name | p70 S6 Kinase β Rabbit Polyclonal Antibody |
| Category | Polyclonal antibody(pAb); Primary antibody |
| Isotype | IgG |
| Purification | Peptide affinity purified |
| About the Immunogen | |
| Immunogen | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to p70 S6 Kinase beta. |
| Gene ID | 6198 |
| SwissProt | P23443 |
| Synonyms | EC 2.7.11.1; KS6B1; P70-S6K; RPS6KB1; Ribosomal protein S6 kinase; Ribosomal protein S6 kinase; 70kDa; polypeptide 1; S6K; kinase p70S6K; p70-S6K |
| Category | PI3K/Akt Signaling |
| Background | p70 S6 kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression. p70 S6 kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5" oligopyrimidine tract mRNAs. A second isoform, p85 S6 kinase, is derived from the same gene and is identical to p70 S6 kinase except for 23 extra residues at the amino terminus, which encode a nuclear localizing signal. Both isoforms lie on a mitogen activated signaling pathway downstream of phosphoinositide-3 kinase (PI-3K) and the target of rapamycin, FRAP/mTOR, a pathway distinct from the Ras/MAP kinase cascade. Ribosomal protein S6 kinase beta-2 is an enzyme that in humans is encoded by the RPS6KB2 gene. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. |
注意事项：
1. 如果本抗体用于Western blot (WB)、免疫荧光(IF)、免疫细胞化学(ICC)等实验，请注意回收使用过的稀释抗体。回收的抗体通常至少可以重复使用5-10次。稀释后的抗体，包括已经使用过的稀释抗体，请4℃保存。
2. 回收后重复使用的抗体，使用方法同新鲜稀释的抗体。如果在重复使用过程中发现抗体出现轻微混浊现象，可以10,000g离心1-3分钟，取上清用于后续检测。如果回收的抗体出现明显的絮状物或长霉长菌等情况，则可以考虑废弃该抗体。
3. 提供的Western一抗稀释液也可以用于免疫荧光(IF)、免疫组化(IHC)、免疫细胞化学(ICC)等适当用途。如果希望获得最佳的检测效果，请考虑使用上述检测专用的一抗稀释液。
储存条件：-20℃，有效期一年。
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文献和实验Measurement of Phosphoinositide 3-Kinase Activity
only PtdIns as a substrate (e.g., mammalian PtdIns 3-kinase and yeast Vps34p) ( 1 ). Generally, PI 3 kinases are now regarded as an important intracellular signal upstream of a variety of biochemical (e.g., activation of Akt/protein kinase B and/or p70
ERK-MAP Kinase Signaling in the Cytoplasm
. We describe two complementary methods for quantitatively measuring ERK activity toward the cytoplasmic p90 ribosomal S6 kinase (RSK). The first method is a straightforward immunoblot of endogenous ERK and RSK phosphoepitopes using phospho-specific antibodies. Infrared
The Extracellular Signal-Regulated Kinase (ERK) Cascade in Neuronal Cell Signaling
The Ras-controlled extracellular signal-regulated kinase (ERK) pathway mediates a large number of cellular events, from proliferation to survival, from synaptic plasticity to memory formation. In order to study the role
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