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上海联迈生物工程有限公司
大量
LM-3934R
多克隆
Rabbit
1年
COX3
细胞色素C氧化酶亚基3抗体
Rabbit
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
KLH conjugated synthetic peptide derived from human COX3:25-130/261
IgG
Lyophilized or Liquid
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
1mg/ml
Store at -20 °C
100ul 200ul
英文名称 | COX3 |
中文名称 | 细胞色素C氧化酶亚基3抗体 |
别 名 | Cytochrome c oxidase polypeptide III; Cytochrome c oxidase subunit 3; COIII; COX3; COX-3; COXIII; MT CO3; MTCO3; COX3_HUMAN; mitochondrially encoded cytochrome c oxidase III; MT-CO3. |
规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
说 明 书 | 100ul 200ul |
研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 信号转导 转录调节因子 线粒体 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, |
产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 30kDa |
细胞定位 | 细胞浆 线粒体 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human COX3:25-130/261 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | Function: Subunits I, II and III form the functional core of the enzyme complex. Subcellular Location: Mitochondrion inner membrane; Multi-pass membrane protein. DISEASE: Leber hereditary optic neuropathy (LHON) [MIM:535000]: A maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiac conduction defects and neurological defects have also been described in some patients. LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes. Note=The disease is caused by mutations affecting the gene represented in this entry. Mitochondrial complex IV deficiency (MT-C4D) [MIM:220110]: A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs. Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness, exercise intolerance, developmental delay, delayed motor development and mental retardation. Some affected individuals manifest a fatal hypertrophic cardiomyopathy resulting in neonatal death. A subset of patients manifest Leigh syndrome. Note=The disease is caused by mutations affecting the gene represented in this entry. Recurrent myoglobinuria mitochondrial (RM-MT) [MIM:550500]: Recurrent myoglobinuria is characterized by recurrent attacks of rhabdomyolysis (necrosis or disintegration of skeletal muscle) associated with muscle pain and weakness, and followed by excretion of myoglobin in the urine. Note=The gene represented in this entry may be involved in disease pathogenesis. Similarity: Belongs to the cytochrome c oxidase subunit 3 family. SWISS: P00414 Gene ID: 4514 Database links: Entrez Gene: 281921 Cow Entrez Gene: 4514 Human Entrez Gene: 17710 Mouse Entrez Gene: 26204 Rat Omim: 516050 Human SwissProt: P00415 Cow SwissProt: P00414 Human SwissProt: P00416 Mouse SwissProt: P05505 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品图片 |
Sample:
kidney(mouse)Lysate at 40 ug Primary: Anti- COX3 (bs-3934R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 30kD Observed band size: 30 kD |
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