KCNA7钾电压阀门通道混合器相关亚家族成员7抗体

KCNA7钾电压阀门通道混合器相关亚家族成员7抗体

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  • ¥780 - 2200
  • LMAI Bio
  • LM-3656R
  • 进口/国产
  • 2025年11月20日
  • WB=1:500-2000 ELISA=1:2000-5000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-3656R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      KCNA7

    • 抗体名

      钾电压阀门通道混合器相关亚家族成员7抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit,

    • 免疫原

      KLH conjugated synthetic peptide derived from human KCNA7:251-350/456

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:2000-5000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      50ul  100ul  200ul

    KCNA7钾电压阀门通道混合器相关亚家族成员7抗体
    英文名称 KCNA7
    中文名称 钾电压阀门通道混合器相关亚家族成员7抗体
    别    名 HAK 6; HAK6; KCNA 7; KV1.7; Potassium voltage gated channel shaker related subfamily member 7; Potassium voltage gated channel subfamily A member 7; Voltage dependent potassium channel Kv1.7; Voltage gated potassium channel KCNA7; Voltage gated potassium channel subunit Kv1.7.  
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 免疫学  神经生物学  通道蛋白  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit, 
    产品应用 WB=1:500-2000 ELISA=1:2000-5000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 50kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human KCNA7:251-350/456 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. The gene is expressed preferentially in skeletal muscle, heart and kidney. It is a candidate gene for inherited cardiac disorders. [provided by RefSeq, Jul 2008]

    Function:
    Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient (By similarity).

    Subunit:
    Heterotetramer of potassium channel proteins.

    Subcellular Location:
    Membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Highly expressed in skeletal muscle, heart and kidney.

    Similarity:
    Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.7/KCNA7 sub-subfamily.

    SWISS:
    Q96RP8

    Gene ID:
    3743

    Database links:

    Entrez Gene: 3743 Human

    Entrez Gene: 16495 Mouse

    Entrez Gene: 365241 Rat

    Omim: 176268 Human

    SwissProt: Q96RP8 Human

    SwissProt: Q17ST2 Mouse

    Unigene: 306973 Human

    Unigene: 12955 Mouse

    Unigene: 218566 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 KCNA7钾电压阀门通道混合器相关亚家族成员7抗体
    Sample: 
    Muscle (Mouse) Lysate at 40 ug
    Primary: Anti-KCNA7 (bs-3656R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 50 kD
    Observed band size: 55 kD

    KCNA7钾电压阀门通道混合器相关亚家族成员7抗体
    Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; 
    Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; 
    Incubation: Anti-KCNA7 Polyclonal Antibody, Unconjugated(bs-3656R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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