CXCL13 B-淋巴细胞趋化因子抗体

CXCL13 B-淋巴细胞趋化因子抗体

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  • ¥780 - 2200
  • LMAI Bio
  • LM-2553R
  • 进口/国产
  • 2025年11月13日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Dog,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-2553R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      CXCL13

    • 抗体名

      B-淋巴细胞趋化因子抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Dog,

    • 免疫原

      KLH conjugated synthetic peptide derived from human CXCL13:23-109/109

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      50ul  100ul  200ul

    CXCL13 B-淋巴细胞趋化因子抗体
    英文名称 CXCL13
    中文名称 B-淋巴细胞趋化因子抗体
    别    名 ANGIE; ANGIE2; B cell attracting chemokine 1; B cell-attracting chemokine 1; B lymphocyte chemoattractant; B-cell chemoattractant; B-cell-attracting chemokine 1; BCA-1; BLC; BLR1L; C-X-C motif chemokine 13; Chemokine (C-X-C motif) ligand 13; Chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant); Chemokine, CXC motif, ligand 13; CXC chemokine BLC; CXCL13; CXL13_HUMAN; SCYB13; Small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant); Small inducible cytokine B13; Small inducible cytokine subfamily B, member 13; Small-inducible cytokine B13.  
    CXCL13 B-淋巴细胞趋化因子抗体 Specific References  (3)     |     bs-2553R has been referenced in 3 publications.
    [IF=8.98] Pei, Guangchang, et al. "Renal Interstitial Infiltration and Tertiary Lymphoid Organ Neogenesis in IgA Nephropathy." Clinical Journal of the American Society of Nephrology (2013): CJN-01150113.  IHC-P ;  Human.  
    PubMed:24262509
    [IF=4.21] Pimenta, Erica Maria, et al. "IRF5 is a novel regulator of CXCL13 expression in breast cancer that regulates CXCR5+ B-and T-cell trafficking to tumor-conditioned media." Immunology and Cell Biology (2014).  other ;  Human.  
    PubMed:25533286
    [IF=2.07] Lemma, Siria A., et al. "Similar chemokine receptor profiles in lymphomas with central nervous system involvement–possible biomarkers for patient selection for central nervous system prophylaxis, a retrospective study." European Journal of Haematology (2015).  IHC-P ;  Human.  
    PubMed:26153511
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 细胞生物  免疫学  趋化因子  b-淋巴细胞  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Dog, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 10kDa
    细胞定位 分泌型蛋白 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human CXCL13:23-109/109 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR1). It may therefore function in the homing of B lymphocytes to follicles.

    Function:
    Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5.

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Highest levels in liver, followed by spleen, lymph node, appendix and stomach. Low levels in salivary gland, mammary gland and fetal spleen.

    Similarity:
    Belongs to the intercrine alpha (chemokine CxC) family.

    SWISS:
    O43927

    Gene ID:
    10563

    Database links:

    Entrez Gene: 10563 Human

    Entrez Gene: 55985 Mouse

    Entrez Gene: 498335 Rat

    Omim: 605149 Human

    SwissProt: O43927 Human

    SwissProt: O55038 Mouse

    Unigene: 100431 Human

    Unigene: 10116 Mouse

    Unigene: 6917 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 CXCL13 B-淋巴细胞趋化因子抗体
    Paraformaldehyde-fixed, paraffin embedded (human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CXCL13) Polyclonal Antibody, Unconjugated (bs-2553R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.

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