产品封面图

TEM1内涎蛋白/内皮唾液酸蛋白抗体

收藏
  • ¥780 - 2200
  • LMAI Bio
  • LM-2101R
  • 进口/国产
  • 2025年07月16日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Mouse, Rat, Dog, Pig, Cow, Horse,
avatar
  • 企业认证

    点击 QQ 联系

    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-2101R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      TEM1

    • 抗体名

      内涎蛋白/内皮唾液酸蛋白抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Pig, Cow, Horse,

    • 免疫原

      KLH conjugated synthetic peptide derived from human TEM 1:251-350/757 <Extracellular>

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      50ul  100ul  200ul

    TEM1内涎蛋白/内皮唾液酸蛋白抗体
    英文名称 TEM1
    中文名称 内涎蛋白/内皮唾液酸蛋白抗体
    别    名 Tumor endothelial marker 1 precursor; TEM 1; TEM-1; tumor endothelial marker 1; CD248; Endosialin; Tumor endothelial marker 1; CD164L1; MGC119478; MGC119479. CD164 sialomucin-like 1; CD248_HUMAN.  
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 肿瘤  心血管  细胞凋亡  生长因子和激素  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 80kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human TEM 1:251-350/757 <Extracellular>
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells. It is believed to play a role in tumor angiogenesis. It is expressed in stromal fibroblasts, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing. TEM1 is being investigated as a potential target for cancer treatment.

    Function:
    May play a role in tumor angiogenesis.

    Subcellular Location:
    Membrane; Single-pass type I membrane protein (Probable).

    Tissue Specificity:
    Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.

    Post-translational modifications:
    O-glycosylated with sialylated oligosaccharides. 
    May be N-glycosylated.

    Similarity:
    Contains 1 C-type lectin domain.
    Contains 1 EGF-like domain.Contains 1 Sushi (CCP/SCR) domain.

    SWISS:
    Q9HCU0

    Gene ID:
    57124

    Database links:

    Entrez Gene: 57124 Human

    Entrez Gene: 70445 Mouse

    Entrez Gene: 293669 Rat

    Omim: 606064 Human

    SwissProt: Q9HCU0 Human

    SwissProt: Q91V98 Mouse

    Unigene: 195727 Human

    Unigene: 29597 Mouse

    Unigene: 38806 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    内皮唾液酸蛋白(CD248)是近年发现的人类肿瘤标记物之一,在人类多种恶性肿瘤组织中异常高表达,内皮唾液酸蛋白对肿瘤细胞生长、血管生成、浸润及转移有重要作用。
    产品图片 产品细节图片1
    Sample:Thymus(mouse) Lysate at 40 ug Primary: Anti-TEM1 (bs-2101R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 80 kD Observed band size: 130 kD
    产品细节图片2
    Sample: spleen(mouse) Lysate at 30 ug
    Primary: Anti-TEM1 (bs-2101R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 80 kD
    Observed band size: 130 kD

    产品细节图片3
    Sample: 
    MKN45(Human) Cell Lysate at 30 ug
    Primary: Anti-TEM1 (bs-2101R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 80 kD
    Observed band size: 130 kD

    产品细节图片4
    Sample: 
    SW480(Human) Cell Lysate at 30 ug
    293T(Human) Cell Lysate at 30 ug
    Primary: Anti-TEM1 (bs-2101R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 80 kD
    Observed band size: 130 kD

    产品细节图片5
    Paraformaldehyde-fixed, paraffin embedded (Human stomach carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TEM1) Polyclonal Antibody, Unconjugated (bs-2101R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

    风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    相关实验
    • 人细胞因子试剂盒

      进口分装 F00610 表皮生长因子受体 (EGFR) ELISA 48T/96T 1200/2000 进口分装 F00611 应急反应生长基因 -1(EGR-1) ELISA 48T/96T 1500/2500 进口分装 F00612 转录因子 E2F1(E2F1) ELISA 48T/96T 2000/3000 进口分装 F00613 内分泌腺性血管内皮因子 (EG-VEGF) ELISA 48T/96T 1800/2800 进口分装 F00614 Elafin

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    ¥980
    温州科淼生物科技有限公司
    2025年07月15日询价
    询价
    上海远慕生物科技有限公司
    2025年06月09日询价
    询价
    上海岑特生物科技有限公司
    2025年07月15日询价
    询价
    上海古朵生物科技有限公司
    2025年05月06日询价
    询价
    上海钰博生物科技有限公司
    2025年07月16日询价
    TEM1内涎蛋白/内皮唾液酸蛋白抗体
    ¥780 - 2200