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上海联迈生物工程有限公司
大量
LM-20579R
多克隆
Rabbit
1年
CACNB1
钙通道电压依赖性β1蛋白抗体
Rabbit
Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
KLH conjugated synthetic peptide derived from human CACNB1:1-100/568
IgG
Lyophilized or Liquid
ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=3μg/Test ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
1mg/ml
Store at -20 °C
100ul 200ul
英文名称 | CACNB1 |
中文名称 | 钙通道电压依赖性β1蛋白抗体 |
别 名 | CAB1; CACNLB1; Calcium channel voltage dependent beta 1 subunit; Voltage dependent L type calcium channel beta 1 subunit; CACB1_HUMAN. |
规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
说 明 书 | 100ul 200ul |
研究领域 | 细胞生物 免疫学 信号转导 转录调节因子 通道蛋白 G蛋白信号 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, |
产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=3μg/Test ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 66kDa |
细胞定位 | 细胞浆 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CACNB1:1-100/568 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | background: The protein encoded by CACNB1 belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Function: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Subunit: The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with JSRP1. Interacts with RYR1 (By similarity). Subcellular Location: Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Tissue Specificity: Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle. Similarity: Belongs to the calcium channel beta subunit family. Contains 1 SH3 domain. SWISS: Q02641 Gene ID: 782 Database links: Entrez Gene: 327703 Cow Entrez Gene: 782 Human Entrez Gene: 12295 Mouse Entrez Gene: 50688 Rat Omim: 114207 Human SwissProt: Q9MZL7 Cow SwissProt: Q02641 Human SwissProt: Q8R3Z5 Mouse SwissProt: P19517 Rabbit SwissProt: P54283 Rat Unigene: 635 Human Unigene: 41252 Mouse Unigene: 9417 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品图片 |
Blank control (blue line): MCF 7 (fixed with 70% methanol (Overnight at 4℃) and then permeabilized with 90% ice-cold methanol for 30 min on ice).
Primary Antibody (green line): Rabbit Anti-CACNB1 antibody (bs-20579R),Dilution: 3μg /10^5 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody (white blue line): Goat anti-rabbit IgG-FITC<,Dilution: 1μg /test. |
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