Recombinant Human LRP-6/Fc Chi

Design of Gene Therapy Clinical Trials in CF Patients

On April 17, 1993, Crystal and co-workers initiated the first human gene therapy trial for cystic fibrosis (CF). In that study, a replication-deficient recombinant adenovirus encoding cystic fibrosis transmembrane conductance regulator (CFTR

Recombinant Antigens in Viral Diagnosis

(CF) assays (2 ). Although these assays can be specific and reliable in the hands of an experienced laboratory worker, they suffer from several significant disadvantages. HI and CF assays are frequently very specific, but are relatively insensitive

Generating NK Cell Receptor-Fc Chimera Proteins from 293T Cells and Considerations of Appropriate Glycosylation

cells. We present here (i) a detailed protocol for the production and purification of soluble recombinant NK cell receptors tagged with human IgG1-Fc (thus termed receptor-Fc chimera or receptor-Ig fusion protein) and (ii) a protocol for cell staining