产品封面图

CD81 antibody

收藏
  • ¥780 - 2200
  • 康朗生物
  • kl-6934R
  • 中国/美国/德国
  • 2026年01月14日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test IF=1:50-200
  • Rabbit
  • Human, Mouse, Dog, Pig, Cow, Horse, Sheep,
avatar
  • 企业认证

    点击 QQ 联系

    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-6934R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      CD81 antibody

    • 抗体名

      CD81抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Dog, Pig, Cow, Horse, Sheep,

    • 免疫原

      KLH conjugated synthetic peptide derived from human TAPA1/CD81:101-210/236 <Extracellular>

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      50ul 100ul 200ul

    CD81 antibody
    中文名称 CD81抗体
    别    名 26 kDa cell surface protein TAPA 1; 26 kDa cell surface protein TAPA-1; 26 kDa cell surface protein TAPA1; CD 81; CD81; CD81 antigen; CD81 molecule; CD81_HUMAN; CVID6; S5.7; TAPA 1; Target of the antiproliferative antibody 1; Tetraspanin 28; Tetraspanin-28; Tetraspanin28; Tspan 28; Tspan-28; Tspan28.  
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 细胞生物  免疫学  信号转导  细菌及病毒  淋巴细胞  b-淋巴细胞  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Dog, Pig, Cow, Horse, Sheep, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test IF=1:50-200 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 26kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human TAPA1/CD81:101-210/236 <Extracellular>
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. [provided by RefSeq, Jul 2008].

    Function:
    May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May acts a the viral receptor for HCV.

    Subunit:
    Plays a critical role in HCV attachment and/or cell entry by interacting with HCV E1/E2 glycoproteins heterodimer. Interacts directly with IGSF8. Interacts with CD53 and SCIMP.

    Subcellular Location:
    Membrane.

    Tissue Specificity:
    Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.

    DISEASE:
    Defects in CD81 are the cause of immunodeficiency common variable type 6 (CVID6); also called antibody deficiency due to CD81 defect. CVID6 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.

    Similarity:
    Belongs to the tetraspanin (TM4SF) family.

    SWISS:
    P60033

    Gene ID:
    975

    Database links:

    Entrez Gene: 975 Human

    Omim: 186845 Human

    SwissProt: P60033 Human

    Unigene: 54457 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 产品细节图片1
    Sample: 
    Spleen (Mouse) Lysate at 40 ug
    Primary: Anti-CD81  (bs-6934R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 26 kD
    Observed band size: 26 kD

    产品细节图片2
    Sample: Lung (Mouse) Lysate at 40 ug
    Primary: Anti-CD81 (bs-6934R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 26 kD
    Observed band size: 25 kD

    产品细节图片3
    Sample: 
    U937(Human) Cell Lysate at 30 ug
    Primary: Anti-CD81  (bs-6934R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 26 kD
    Observed band size: 26 kD

    产品细节图片4
    Sample: 
    Jurkat(Human) Cell Lysate at 30 ug
    Primary: Anti-CD81  (bs-6934R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 26 kD
    Observed band size: 26 kD

    产品细节图片5
    Tissue/cell: human rectal carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; 
    Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; 
    Incubation: Anti-TAPA1/CD81 Polyclonal Antibody, Unconjugated(bs-6934R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

    产品细节图片6
    Blank control(blue): Jurkat cells(fixed with 2% paraformaldehyde (10 min)). 
    Primary Antibody:Rabbit Anti-CD81 antibody(bs-6934R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; 
    Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); 
    Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.

    产品细节图片7
    Blank control: Mouse Brain cells(blue). 
    Primary Antibody: Rabbit Anti- CD81 /PEConjugated antibody (bs-6934R-PE), Dilution: 5μg in 100 μL 1X PBS containing 0.5% BSA; 
    Isotype Control Antibody: Rabbit IgG/PE(orange) ,used under the same conditions.

    风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    相关实验
    • CD81分子

      CD81 分子   CD81 常用单克隆抗体或代号: ID6,5A6;(TAPA- 1) 主要表达细胞: 广泛,包括B,T,M [B] 分子质量(kDa)和结构: p26(TM4-SF) 功    能: 增殖抗体靶抗原,与CD19、CD21相连,组成B细胞复合体   CD81 Aka Target of an Anti-Proliferative Antibody (TAPA1)

    • Generation of Antibody Molecules Through Antibody Engineering

      been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional

    • CD19/CD81白细胞分化抗原及其功能

      CD19 / CD81 白细胞分化抗原及其功能       CDl9  CDl9分子胞膜外区结构属IgSF,包括2个C2样区,胞质区较长,不同种属间有很高的同源性,含有可发生磷酸化的丝/苏氨酸和酪氨酸残基。CDl9分子分布于除浆细胞外的B细胞谱系发育的各个阶段,也是与B细胞识别、黏附和活化有关的CD分子的结构B细胞的重要标记。       此外CDl9还表达于生发中心的FDC,以及某些急性髓细胞白血病细胞。CDl9是CDl9/CD21/CD81信号复合

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    ¥2062
    武汉维克赛思科技有限公司
    2025年07月10日询价
    ¥22
    艾美捷科技有限公司
    2025年07月10日询价
    询价
    武汉佰瑞得生物技术有限公司
    2025年07月13日询价
    ¥1320
    武汉华美生物工程有限公司CUSABIO®
    2025年06月22日询价
    ¥5600
    GeneTex
    2025年07月13日询价
    CD81 antibody
    ¥780 - 2200