相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海联迈生物工程有限公司
- 库存:
大量
- 目录编号:
LM-14239R
- 克隆性:
多克隆
- 抗原来源:
Rabbit
- 保质期:
1年
- 抗体英文名:
DDX6
- 抗体名:
ATP依赖RNA解旋酶DDX6抗体
- 宿主:
Rabbit
- 适应物种:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,
- 免疫原:
KLH conjugated synthetic peptide derived from human DDX6:51-150/483
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
- 浓度:
1mg/ml
- 保存条件:
Store at -20 °C
- 规格:
100ul 200ul
| 英文名称 | DDX6 |
| 中文名称 | ATP依赖RNA解旋酶DDX6抗体 |
| 别 名 | ATP dependent RNA helicase DDX6; ATP dependent RNA helicase p54; DDX6; DEAD (Asp Glu Ala Asp) box polypeptide 6; DEAD box 6; DEAD box protein 6; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA helicase 54kD); FLJ36338; HLR2; Oncogene RCK; P54; Probable ATP-dependent RNA helicase DDX6; RCK. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 细胞凋亡 转录调节因子 细胞分化 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 54kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DDX6:51-150/483 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012] Function: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis and cellular growth and division. In the process of mRNA degradation, DDX6 may play a role in mRNA decapping. It forms a complex with DCP1A, DCP2, EDC3 and EDC4/HEDLS. Subcellular Location: Cytoplasm; P-body. Note: Processing bodies (PB). SWISS: P26196 Gene ID: 1656 Database links: Entrez Gene: 1656 Human Entrez Gene: 13209 Mouse Entrez Gene: 500988 Rat Omim: 600326 Human SwissProt: P26196 Human SwissProt: P54823 Mouse Unigene: 408461 Human Unigene: 267061 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验师从施一公,发表 6 篇Science/3篇 Cell,她被誉为「世界最具潜力女科学家」| 论文盘点
分辨率为 3.5 埃。内含子套索仍然结合在剪接体中,而连接的外显子已经解离。步骤 II 剪接因子 Prp17 和 Prp18 以及稳定与 U5 小核 RNA(SnRNA)环 I 结合的 5’外显子的 Cwc21 和 Cwc22 已经从活性位点组装中释放。 Deah 家族 ATP 酶/解旋酶 Prp43 与剪接体外围的 Syf1 结合,其 RNA 结合位点接近 U6snRNA 的 3’端。Ntr1 /Spp382 的 C-末端结构域与 GTPase Snu114 结合,而 Ntr2 与 Ntr1 的超
相关专题 1、Dicer酶 在RNA干扰研究中会用到Dicer酶,Dicer酶是RNaseIII型家族中的蛋白酶,可特异识别dsRNA,它可以切割以各种方式进入到细胞内的dsRNA,将其切割成19-21bp大小的短RNAs。 Dicer是来自果蝇RNA干扰必须的RNaseIII型蛋白。Dicer酶是RNase III家族中特异识别双链RNA的一员,它能以一种ATP依赖的方式逐步切割由外源导入或者由转基因
),是识别靶RNA的标志。siRNA的生成启动了RNAi反应。 2)效应阶段:siRNA结合一个核酶复合物,形成所谓的RNA诱导的沉默复合物(RNA-induce silencing complex,RISC)。这个核酶复合物由内切 核酸酶 、外切核酸酶、解旋酶和同源RNA搜索活性蛋白四种成分组成。激活该复合物需要一个ATP依赖的将siRNA解双链的过程,活化以后的RISC定位到与siRNA中的反义链互补的靶mRNA转录本上,并在距离siRNA3 ’端12个碱基
技术资料暂无技术资料 索取技术资料










