GABRA5 antibody

GABRA5 antibody

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  • ¥780 - 2200
  • 康朗生物
  • kl-6708R
  • 中国/美国/德国
  • 2025年11月28日
  • WB=1:500-2000 ELISA=1:500-1000
  • Rabbit
  • Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
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    • 详细信息
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-6708R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      GABRA5 antibody

    • 抗体名

      γ1氨基丁酸受体α5/GABRα5抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,

    • 免疫原

      KLH conjugated synthetic peptide derived from human GABRA5:201-300/462 <Extracellular>

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      50ul 100ul 200ul

    GABRA5 antibody
    中文名称 γ1氨基丁酸受体α5/GABRα5抗体
    别    名 GBRA5_HUMAN; GAA 5; GAA5; GABRA 5; GABRA5; Gamma aminobutyric acid GABA A receptor alpha 5; Gamma aminobutyric acid GABA A receptor alpha 5 precursor; Gamma aminobutyric acid receptor alpha 5 subunit precursor GABA A receptor.  
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 细胞生物  神经生物学  信号转导  细胞膜受体  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 47kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human GABRA5:201-300/462 <Extracellular>
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non coding first exons have been described.

    Function:
    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

    Subunit:
    Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.

    Subcellular Location:
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

    Similarity:
    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA5 sub-subfamily.

    SWISS:
    P31644

    Gene ID:
    2558

    Database links:

    Entrez Gene: 523515 Cow

    Entrez Gene: 2558 Human

    Entrez Gene: 110886 Mouse

    Entrez Gene: 29707 Rat

    Omim: 137142 Human

    SwissProt: Q08E50 Cow

    SwissProt: P31644 Human

    SwissProt: Q8BHJ7 Mouse

    SwissProt: P19969 Rat

    Unigene: 24969 Human

    Unigene: 273114 Mouse

    Unigene: 10368 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 GABRA5 antibody
    Sample: 
    U2os Cell (Human) Lysate at 30 ug
    Primary: Anti-GABRA5 (bs-6708R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 47 kD
    Observed band size: 48 kD

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