hNTKL BP1; N terminal kinase like binding protein 1; NTKL binding protein 1; NTKL BP1; NTKLBP 1; NTKLBP1; SCY1 like 1 binding protein 1; SCYL1 binding protein 1; SCYL1 BP1; GORAB_HUMAN.
规格价格
100ul/1380元 购买 200ul/2200元 购买 大包装/询价
说 明 书
100ul 200ul
研究领域
细胞生物 信号转导
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
产品应用
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
45kDa
细胞定位
细胞浆
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human SCYL1BP1:201-300/394
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed
PubMed
产品介绍
background: Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.
Subunit: Interacts with SCYL1 (By similarity). Interacts with RCHY1 and RAB6A/RAB6.
Subcellular Location: Cytoplasm. Golgi apparatus.
DISEASE: Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.
Similarity: Belongs to the GORAB family.
SWISS: Q5T7V8
Gene ID: 92344
Database links:
Entrez Gene: 92344 Human
Entrez Gene: 98376 Mouse
Entrez Gene: 304923 Rat
Omim: 607983 Human
SwissProt: Q5T7V8 Human
SwissProt: Q8BRM2 Mouse
SwissProt: B1H222 Rat
Unigene: 183702 Human
Unigene: 32901 Mouse
Unigene: 45710 Rat
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片
Sample: HepG2 Cell (Human) Lysate at 40 ug Primary: Anti-SCYL1BP1 (bs-6643R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 55 kD