SLC40A1 antibody

SLC40A1 antibody

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  • ¥780 - 2200
  • 康朗生物
  • kl-3579R
  • 中国/美国/德国
  • 2025年07月11日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-F=1:400-800 IF=1:100-500
  • Rabbit
  • Human, Mouse, Rat, Dog, Pig, Rabbit,
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    • 详细信息
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-3579R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      SLC40A1 antibody

    • 抗体名

      细胞膜铁转运蛋白FP1抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Pig, Rabbit,

    • 免疫原

      KLH conjugated synthetic peptide derived from human SLC40A1:201-300/571

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-F=1:400-800 IF=1:100-500

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      50ul 100ul 200ul

    SLC40A1 antibody
    中文名称 细胞膜铁转运蛋白FP1抗体
    别    名 Ferroportin 1; Ferroportin-1; FPN1; HFE4; IREG1; Iron regulated transporter 1; Iron-regulated transporter 1; MTP1; S40A1_HUMAN; SLC40A1; Solute carrier family 40 member 1; MST079; MSTP079; MTP1; SLC11A3.  
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 肿瘤  免疫学  信号转导  转录调节因子  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Pig, Rabbit, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 63kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human SLC40A1:201-300/571 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin.

    Function:
    May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein. Note=Localized to the basolateral membrane of polarized epithelial cells.

    Tissue Specificity:
    Expressed in placenta, intestine, muscle and spleen.

    DISEASE:
    Defects in SLC40A1 are the cause of hemochromatosis type 4 (HFE4) [MIM:606069]. HFE4 is an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin before elevation of the transferrin saturation.

    Similarity:
    Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.

    SWISS:
    Q9NP59

    Gene ID:
    30061

    Database links:

    Entrez Gene: 30061 Human

    Entrez Gene: 53945 Mouse

    Entrez Gene: 170840 Rat

    Omim: 604653 Human

    SwissProt: Q9NP59 Human

    SwissProt: Q9JHI9 Mouse

    SwissProt: Q923U9 Rat

    Unigene: 643005 Human

    Unigene: 28756 Mouse

    Unigene: 15324 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 SLC40A1 antibody
    Sample: 
    Embryo (Mouse) Lysate at 40 ug
    Primary: Anti-SLC40A1 (bs-3579R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 63 kD
    Observed band size: 63 kD

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