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- 详细信息
- 文献和实验
- 技术资料
- 库存:
757
- 英文名:
Recombinant Human Tumor Necrosis Factor alpha
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冻干蛋白置于-20℃以下可长期保存,室温
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括重组人TNFα(TNFSF2)厂家价格在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。
名称:重组人TNFα(TNFSF2)厂家价格
编号:JN0438
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Human Tumor Necrosis Factor alpha
品牌:百奥莱博
产地:北京
本品由我们的大肠杆菌表达系统制备而成。
TNFa/TNFSF2 (high active)质量控制:>95%(还原性SDS-PAGE)
TNFa/TNFSF2 (high active)制剂:冻干品
TNFa/TNFSF2 (high active)保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
TNFa/TNFSF2 (high active)复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于TNFa/TNFSF2 (high active):
Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-α while cells that express CD8 secrete little or no TNF-α. Synthesis of TNF-α can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumor activity of TNF-α has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF-α mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF-α that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumor activity and reduced systemic toxicity in mice comp*(代"a")red with murine TNF-α, which binds to both murine TNF receptors. Based on these results, many TNF-α mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumor cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF-α High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.
关于重组人TNFα(TNFSF2)厂家价格的更详细说明,请致电我公司咨询,我们将以最饱满的热情为您提供解答,此外,我公司专业供应下列产品:
·重组人ECH1
编号:JN1388
英文名称:Recombinant Human Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Thr34-Leu328在N端含有His标签。
ECH1质量控制:>95%(还原性SDS-PAGE)
ECH1制剂:液体
ECH1保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于ECH1:
Human delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase(ECH1) is a member of the hydratase/isomerase superfamily and contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The rat orthologlocalizes to the matrix of both the peroxisome and mitochondria.It can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. ECH1 plays an important role in the auxiliary step of the fatty acid beta-oxidation pathway.
重组人TNFα(TNFSF2)厂家价格关键词:重组TNFα,重组人TNFα,JN0438,重组人TNFα蛋白,重组人TNFSF2
SV0882 OneTaq 热启动 Quick-Load 2X Master Mix(提供 GC 缓冲液)
WE0317 水性封片剂 Mounting Solution(Aqueous)
KFS061 SDS-PAGE电泳液(干粉)
SY0288 硫*(代"酸")卡那霉素 Kanamycin Sulfate
RFT183 壮观霉素溶液(50mg/ml) Spectinomycin solution
KFS261 细胞核染料PI染色液(即用型)
HR0057 植物根茎蛋白提取试剂盒 Plant stem protein extraction kit
YT875 封闭液(用TBS配置,含吐温20) Blocking Buffer(TBS)
BTN130430 大肠杆菌DNA聚合酶Ⅰ E.coli DNA Polymerase I
HR0444 活细胞/死细胞双染试剂盒 Living cell/dead cell double staining kit
SV1425 抗 MBP 单克隆抗体
YT224 HIF-1α凝胶迁移探针(10μM) HIF-1α Probe For EMSA(10μM)
BTN120515 即用型蓝白T载体E型(无RNA启动子,无MCS) Instant Blue-White Vector T,Type E
SY0547 支原体去除试剂(1000×) Treatment (1000×)-Mycoplasma Elimination Reagent
SV0627 PvuI-HF限制性内切酶 PvuI-HF Restriction Endonuclease
WE0213 DNase I(不含RNase) DNase I(RNase Free)
BTN60403 红细胞裂解液A型(核酸纯化) Red Cell Lysis Solution,Type A
SY0184 C/EBPα-GFP报告基因质粒 C/EBPα GFP Reporter Plasmid
重组人TNFα(TNFSF2)厂家价格关键词:重组TNFα,重组人TNFα,JN0438,重组人TNFα蛋白,重组人TNFSF2
·重组人载脂蛋白E(ApoE)
编号:JN1227
英文名称:Recombinant Human Apolipoprotein E
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Lys19-His317在C端含有His标签。
Apolipoprotein E/ApoE质量控制:>95%(还原性SDS-PAGE)
Apolipoprotein E/ApoE制剂:冻干品
Apolipoprotein E/ApoE保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Apolipoprotein E/ApoE复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Apolipoprotein E/ApoE:
ApoE, a glycoprotein, is a structural component of very low density lipoprotein (vLDL) synthesized by the liver and intestinally synthesized chylomicrons . ApoE is also a constituent of a subclass of high density of lipoproteins (HDL) involved in cholesterol transport .ApoE mediates high affinity binding of chylomicrons and vLDL particles to the LDL receptor, allowing for specific uptake of these particles by the liver, preventing the accumulation of cholesterol rich particles in the plasma .Apolipoprotein E combines with fats (lipids) in the body to form molecules called lipoproteins and Apolipoprotein E is a major component of a specific type of lipoprotein called very low-density lipoproteins (VLDLs).
我公司正在火爆促销重组蛋白系列产品,欢迎您的垂询选购重组人TNFα(TNFSF2)厂家价格。
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文献和实验年耿信笃教授首先将高效疏水相互作用色谱(HPHIC)用于变性蛋白的复性,很好的解决了上述问题,现已成功用于重组人干扰素-g(rhIFN-g)、重组人干扰素-a(rhIFN-a)、人粒细胞集落刺激因子(rhG-CSF)、重组人胰岛素原(proinsulin)、重组牛朊病毒(prion)等重组蛋白以及溶菌酶和核搪核酸酶等标准模型蛋白的复性与同时纯化中。目前,排阻色谱法、离子交换色谱法和亲合色谱法也已用于蛋白质的复性和同时纯化中。与传统的稀释法及透析法比较,用色谱法进行蛋白复性的优点是:①在进样后可很快
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