- ¥780 - 2200
- LMAI Bio
- LM-0044R
- 进口/国产
- 2025年07月12日
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
- Rabbit
- Human, Mouse, Rat,
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海联迈生物工程有限公司
- 库存：
大量
- 目录编号：
LM-0044R
- 克隆性：
多克隆
- 抗原来源：
Rabbit
- 保质期：
1年
- 抗体英文名：
BNP
- 抗体名：
脑钠素/利钠肽抗体
- 宿主：
Rabbit
- 适应物种：
Human, Mouse, Rat,
- 免疫原：
KLH conjugated synthetic peptide derived from human BNP 32 (103-120aa):103-120/134
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
- 浓度：
1mg/ml
- 保存条件：
Store at -20 °C
- 规格：
50ul 100ul 200ul
BNP脑钠素/利钠肽抗体
| 英文名称 | BNP |
| 中文名称 | 脑钠素/利钠肽抗体 |
| 别 名 | BNP 32; Brain natriuretic peptide 32; Gamma brain natriuretic peptide; Natriuretic peptide brain type; Natriuretic peptide precursor B; Natriuretic peptides B; NPPB; NPPB protein; ANFB_HUMAN; Natriuretic peptides B.proBNP. |
| 规格价格 | 50ul/780元 购买 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 50ul 100ul 200ul |
| 研究领域 | 心血管 信号转导 生长因子和激素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 3.5kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BNP 32 (103-120aa):103-120/134 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity Function: Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. Subcellular Location: Secreted. Tissue Specificity: Brain and also in atria, but at much lower levels than ANP. Similarity: Belongs to the natriuretic peptide family. SWISS: P16860 Gene ID: 4879 Database links: Entrez Gene: 4879 Human Omim: 600295 Human SwissProt: P16860 Human Unigene: 219140 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 脑钠素主要是心脏激素，心脏作为内分泌器官释放脑钠素，调解体液及电解质内环境的恒定性。 B型利钠肽（钠尿肽）（B－typenatriureticpeptide，BNP），又称脑钠素或脑钠肽，因其有排钠利尿、内皮非依赖性的血管平滑肌作用而具有降压、抗心肌纤维化、影响神经内分泌系统等功效。 近来发现BNP在各种心血管疾病，尤其是心室功能不全、急性心肌梗死（ami）、高血压等疾病的诊断、治疗及预后等方面有重要意义，已引起临床工作者的高度重视。 |
| 产品图片 |
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-BNP Polyclonal Antibody, Unconjugated(bs-0044R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining 
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-BNP Polyclonal Antibody, Unconjugated(bs-0044R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining 
Tissue/cell: mouse kidney tissue;4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-BNP Polyclonal Antibody, Unconjugated(bs-0044R) 1:200, overnight at 4°C; The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated(bs-0295G-Cy3)used at 1:200 dilution for 40 minutes at 37°C. DAPI(5ug/ml,blue,C-0033) was used to stain the cell nuclei |
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文献和实验相关实验
人脑钠素/ 脑钠尿肽（BNP ） 酶联免疫分析 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中脑钠素/ 脑钠尿肽（BNP ） 的含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本中人脑钠素 / 脑钠尿肽（ BNP ） 水平。用纯化的人脑钠素 / 脑钠尿肽（ BNP ） 抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入脑钠素 / 脑钠尿肽（ BNP
犬脑钠素（BNP） 酶联免疫 分析 试剂 盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定犬血清，血浆及相关液体样本中 脑钠素（BNP） 的含量。 实验原理 ： 本试剂盒应用双抗体夹心法测定 标本 中 犬 脑素（BNP ） 水平。用纯化的 犬 脑钠素（BNP ） 抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入 脑钠素（BNP ）， 再与HRP 标记的 脑钠素（BNP ） 抗体结合，形成抗体
分离的，所以乳名叫脑钠肽。 这个发现随即在大名鼎鼎的 Nature 杂志上发表。猪们很兴奋，可是它们并没有高兴多久，1991 年 Mukoyama 等发现实际上 BNP 在很多脏器都可以分泌，而主要其实是由心室分泌。 随后 10 年中 BNP 一直是生物学界研究的热点。其名称繁多，不但叫脑钠肽，也可以叫脑钠素、脑利尿钠肽、脑利钠肽、Ｂ型钠利尿肽、Ｂ型钠尿肽、Ｂ型促尿钠排泄肽、Ｂ钠尿肽，但最正规的命名应该是-----Ｂ型利钠肽（BNP）。看到同一个物质在我国能有这么多合法马甲，我和我的小伙伴们都惊呆
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BNP脑钠素/利钠肽抗体
¥780 - 2200
