CD62P (P-Selectin) Monoclonal

CD62P (P-Selectin) Monoclonal Antibody (AK-4), PE, eBioscience™

货号 12-0628-42

100 Tests

产品描述
Description: The AK-4 monoclonal antibody reacts with human CD62P, a 140 kDa transmembrane glycoprotein also known as P-Selectin. Upon activation, CD62P is rapidly transported from its cytoplasmic stores in the Weibel-Palade bodies of endothelial cells or the alpha-granules of platelets to the surface. CD62P initiates the adhesive interaction between endothelial cells and neutrophils and monocytes during the inflammatory reaction and is also involved in the interaction of platelets with monocytes and neutrophils.

Applications Reported: The AK-4 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This AK-4 antibody has been pre-titrated and tested by flow cytometric analysis of resting and thrombin-activated human platelets. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.

Filtration: 0.2 µm post-manufacturing filtered.

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