- ¥1380 - 2200
- 康朗生物
- kl-12029R
- 中国/美国/德国
- 2025年07月11日
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500
- Rabbit
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
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- 详细信息
- 技术资料
- 供应商：
上海康朗生物科技有限公司
- 库存：
大量
- 目录编号：
kl-12029R
- 克隆性：
多克隆
- 抗原来源：
Rabbit
- 保质期：
12个月
- 抗体英文名：
GPRC5B antibody
- 抗体名：
G蛋白偶联受体C5B抗体
- 宿主：
Rabbit
- 适应物种：
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 免疫原：
KLH conjugated synthetic peptide derived from human G protein coupled receptor family C group 1 member B:1-100/403 <Extracellular>
- 亚型：
IgG
- 形态：
冻干粉或液体
- 应用范围：
ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500
- 浓度：
1mg/ml
- 保存条件：
-20 °C
- 规格：
100ul 200ul
GPRC5B antibody
| 中文名称 | G蛋白偶联受体C5B抗体 |
| 别 名 | A 69G12.1; A-69G12.1; G protein coupled receptor family C group 1 member B; G protein coupled receptor family C group 5 member B; G-protein coupled receptor family C group 5 member B; GPC5B_HUMAN; Gprc5b; LOC51704; RAIG-2; RAIG2; Retinoic acid responsive gene protein; Retinoic acid-induced gene 2 protein; GPCR GPRC5B. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 42kDa |
| 细胞定位 | 细胞浆 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human G protein coupled receptor family C group 1 member B:1-100/403 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: GPRC5B (G protein-coupled receptor family C group 5 member B, retinoic acid-induced gene 2 protein) is a 403 amino acid protein encoded by the human GPRC5B gene. GPRC5B is an orphan receptor member of the G protein-coupled receptor 3 family. G protein-coupled receptors (GPCRs or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. Key roles for G protein-coupled receptors include control of protein maturation and cell surface delivery, and providing the correct framework for interactions with both heterotrimeric G proteins and arrestins to allow signal generation and termination. This retinoic acid-inducible G protein-coupled receptor provides evidence for a possible interaction between retinoid and G protein signaling pathways. GPRC5B is highly expressed in kidney, pancreas and testis, and has moderate expression in brain, heart, prostate, small intestine and spleen. Function: Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Subcellular Location: Cell membrane. Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles. Tissue Specificity: Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal chord as well as in dorsal root ganglia (DRG). In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach. Similarity: Belongs to the G-protein coupled receptor 3 family. SWISS: Q9NZH0 Gene ID: 51704 Database links: Entrez Gene: 51704 Human Entrez Gene: 64297 Mouse Entrez Gene: 293546 Rat Omim: 605948 Human SwissProt: Q9NZH0 Human SwissProt: Q923Z0 Mouse Unigene: 148685 Human Unigene: 103439 Mouse Unigene: 47330 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 |
Positive control: (mo)Splenocytes(2% Paraformaldehyde-fixed )
Isotype Control Antibody: Rabbit IgG; Dilution: 1μg in 100 μl 1 X PBS containing 0.5% BSA Secondary Antibody: Goat anti-rabbit IgG-FITC; Dilution: 1:200 in 1 X PBS containing 0.5% BSA Primary Antibody: rabbit Anti-GPRC5B (bs-12029R); Dilution: 1μg in 100 μl 1X PBS containing 0.5% BSA |
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GPRC5B antibody
¥1380 - 2200
