重组Fpg(甲酰氨基嘧啶DNA糖基化酶)北京厂家现货

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖重组Fpg(甲酰*基嘧啶DNA糖基化酶)北京厂家现货在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：重组Fpg(甲酰*基嘧啶DNA糖基化酶)北京厂家现货
产地：国产|进口
编号：JN1936
品牌：百奥莱博
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目标蛋白包含Met1-Lys269序列。

Fpg质量控制：＞95%(SEC-HPLC，还原性SDS-PAGE)


Fpg制剂：液体

Fpg保存：
收到后请置于-20℃以下，可保存长达6个月，避免反复冻融。

关于Fpg：
Fpg is a DNA glycosylase that releases damaged bases preferentially from duplex DNA. It has an associated class I AP (apurinic/apyrimidinic) lyase activity.Fpg Cleaves the DNA backbone to generate a single-strand break at the site of the removed base, The C-O-P bond 3 to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving 3 and 5 phosphoryl groups.

重组Fpg(甲酰*基嘧啶DNA糖基化酶)北京厂家现货极具性价比，此外，我公司正火爆促销以下产品：

·重组小鼠Acrp30(30kD脂肪细胞补体相关蛋白)
编号：JN1276
英文名称：Recombinant Mouse Adipocyte complement-related 30 kDa protein
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu18-Asn247在C端含有His标签。

Acrp30质量控制：＞95%(还原性SDS-PAGE)

Acrp30制剂：冻干品

Acrp30保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Acrp30复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Acrp30：
Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.


重组Fpg(甲酰*基嘧啶DNA糖基化酶)北京厂家现货关键词：重组甲酰*基嘧啶DNA糖基化酶,JN1936,重组Fpg蛋白


·重组人TNFα(TNFSF2)
编号：JN0438
英文名称：Recombinant Human Tumor Necrosis Factor alpha
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成。

TNFa/TNFSF2 (high active)质量控制：＞95%(还原性SDS-PAGE)


TNFa/TNFSF2 (high active)制剂：冻干品

TNFa/TNFSF2 (high active)保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TNFa/TNFSF2 (high active)复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TNFa/TNFSF2 (high active)：
Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-α while cells that express CD8 secrete little or no TNF-α. Synthesis of TNF-α can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumor activity of TNF-α has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF-α mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF-α that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumor activity and reduced systemic toxicity in mice comp*(代"a")red with murine TNF-α, which binds to both murine TNF receptors. Based on these results, many TNF-α mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumor cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF-α High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.



重组Fpg(甲酰*基嘧啶DNA糖基化酶)北京厂家现货关键词：重组甲酰*基嘧啶DNA糖基化酶,JN1936,重组Fpg蛋白

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北京百莱博科技有限公司专业生产重组蛋白产品，欢迎来电咨询选购重组Fpg(甲酰*基嘧啶DNA糖基化酶)北京厂家现货。