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- 详细信息
- 文献和实验
- 技术资料
- 库存:
879
- 英文名:
Recombinant Human Programmed Cell Death 1 Ligand 1
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冻干蛋白置于-20℃
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博主要从事生物试剂的生产和销*(代"售"),产品线涵盖北京现货重组人PD-L1(B7-H1)特价优惠在内的分子生物学试剂产品,还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。
名称:北京现货重组人PD-L1(B7-H1)特价优惠
英文名:Recombinant Human Programmed Cell Death 1 Ligand 1
品牌:百奥莱博
编号:JN1462
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Phe19-Thr239在C端带mFc标签。
PD-L1/B7-H1质量控制:>95%(还原性SDS-PAGE)
PD-L1/B7-H1制剂:冻干品
PD-L1/B7-H1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
PD-L1/B7-H1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于PD-L1/B7-H1:
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.
北京现货重组人PD-L1(B7-H1)特价优惠正在火爆热销,除此之外,为您推荐下别热销产品:
·重组人白介素IL-10(白细胞介素10)
编号:JN0380
英文名称:Recombinant Human Interleukin-10
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备,目的基因编码的Ser19-Asn178表达纯化而来。
IL-10质量控制:>95%(还原性SDS-PAGE)。
IL-10制剂:冻干品
IL-10保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-10复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-10:
Interleukin 10(IL10), also known as cytokine synthesis inhibitory factor (CSIF),is a secreted protein and belongs to the IL-10 family. IL-10 is secreted by many activated hematopoietic cell types as well as hepatic stellate cells, keratinocytes, and placental cytotrophoblasts . IL-10 is an anti-inflammatory TH2 cytokine that has a critical role in limiting the immune response to pathogens to prevent host damage. As IL-10 in produced in several T helper populations, it is proposed that it provides a feedback loop to limit the effector functions of macrophages and DCs on T cells. Once expressed, IL-10 signals through the IL-10 receptor (IL-10R) to activate STAT3. As IL-10 is a strong inhibitor of inflammation, it has become a viable biomarker for various diseases and conditions as well as a therapeutic molecule for certain conditions. In addition to elevated levels in parasitic infection, high expression levels of IL-10 are also found in retroviral infections inducing immunodeficiency. The immunosuppressive properties of IL-10 suggest a possible clinical use of IL-10 in suppressing rejections of grafts after organ transplantations
北京现货重组人PD-L1(B7-H1)特价优惠关键词:JN1462,重组人B7-H1,重组人PD-L1,重组人PD-L1蛋白,重组PD-L1
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北京现货重组人PD-L1(B7-H1)特价优惠关键词:JN1462,重组人B7-H1,重组人PD-L1,重组人PD-L1蛋白,重组PD-L1
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我公司生产供应销*(代"售")的重组蛋白产品正全系列现货促销,满分期待您的垂询选购北京现货重组人PD-L1(B7-H1)特价优惠。
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验被 PeterLinsley 鉴定,而且免疫抑制功能也是在 1994 年被 Jeffrey Bluestone 发现。但Allison 始终对外宣称他是发明了 CTLA-4 抗体治疗肿瘤的。James Allison 与他自己牌照为CTLA-4的保时捷 911 跑车而陈列平教授率先克隆并鉴定了 B7-H1 分子(即现在的 PD-L1)做出的开创工作(1999 年)。陈列平教授率先证明了 B7-H1 蛋白在许多人肿瘤里大量地表达,为临床试验奠定基础(2002 年)。Tasuku Honjo 这时才开始了解到 10 年前
和非组蛋白相关抗体,相关蛋白的修饰化抗体,如甲基化,乙酰化,去乙酰化,磷酸化。抗体价格优惠,性价比高:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000。绝大部分抗体国内现货,及时快捷的为老师提供优质抗体。完善及时的售后服务为老师解决抗体使用的后顾之忧。 ImmunoWay 公司有着自己独特的产品 Cell Based Elisa,适合
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