- ¥464
- 联迈生物
- LM7343-2μg
- 中国/上海
- 2025年07月13日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
大量
- 英文名：
Recombinant Murine Bcl-xL
- 保质期：
一年
- 供应商：
上海联迈生物工程有限公司
- 保存条件：
-20℃或更低温度保存
- 规格：
2μg
| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| LM7343-2μg | Recombinant Murine Bcl-xL | 2μg | 464.00元 |
| Species | Gene ID | Accession | Source | Length | MW | Tag |
| Mouse | 12048 | LM64373 | E. coli | 211aa | 23.7kDa | － |
| About this Antibody | |
| Name | Recombinant Murine Bcl-xL (Recombinant Murine B-cell Lymphoma-extra Large; rMuc)；Recombinant Mouse Bcl-xL ; 重组小鼠B细胞淋巴瘤xL |
| Synonyms | Apoptosis regulator Bcl-X; bcl2-L-1; Bcl2-L-1; BCL2-like 1; bcl-2-like protein 1; BCLXBCL2LBcl-X; BCLXL; bcl-xL; BCL-XL/S; BCLXS; bcl-xS; DKFZLM781P2092 |
| Purity | >97% by SDS-PAGE and HPLC analyses. |
| Biological Activity | Test in Process. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Lyophilized from a 0.2μm filtered concentrated solution in 2X PBS, pH7.4, 5% Trehalose. |
| Endotoxin | Less than 0.1EU/μg of rMuBcl-xL as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
| Category | Others |
| Background | Bcl-X, also named as BCL2L1 or BCL2L, belongs to the Bcl-2 family and is encoded by the BCL2L1 gene in human. Alternative splicing of Bcl-X results in at least two isoforms，isoform Bcl-X(L) (also named as Bcl-xL) and isoform Bcl-x(S) (also named as Bcl-xS). Bcl-xL is found in tissues containing long-lived postmitotic cells, such as adult brain, while Bcl-xS is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. Bcl-X forms homodimer or heterodimer with other Bcl-2 proteins, like BAK, BAX or Bcl-2, to act as anti- or pro- apoptotic regulators. Bcl-xL appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane, and it also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. In contrast, Bcl-xS is a pro-apoptotic protein that promotes apoptosis. |
| Amino Acid Sequence | SQSNRELVVD FLSYKLSQKG YSWSQFSDVE ENRTEAPEET EAERETPSAI NGNPSWHLAD SPAVNGATGH SSSLDAREVI PMAAVKQALR EAGDEFELRY RRAFSDLTSQ LHITPGTAYQ SFEQVVNELF RDGVNWGRIV AFFSFGGALC VESVDKEMQV LVSRIASWMA TYLNDHLEPW IQENGGWDTF VDLYGNNAAA ESRKGQERFN R |
| 产品编号 | 产品名称 | 包装 |
| LM7343-2μg | Recombinant Murine Bcl-xL | 2μg |
| LM7343-10μg | Recombinant Murine Bcl-xL | 10μg |
| LM7343-100μg | Recombinant Murine Bcl-xL | 100μg |
| LM7343-1mg | Recombinant Murine Bcl-xL | 1mg |
| - | 说明书 | 1份 |
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
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