Recombinant Human CyP-D (Recombinant Human Cyclophilin D; rHuCyP-D);重组人亲环素D
Synonyms
OI9; CYPB; SCYLP; CYP-S1; HEL-S-39
Purity
>95% by SDS-PAGE and HPLC analyses.
Biological Activity
Data Not Available.
Physical Appearance
Sterile colorless liquid.
Formulation
Supplied as a 0.2μm filtered solution in PBS, pH 7.4, with 1mM DTT, 10% glycerol.
Endotoxin
Less than 0.1EU/μg of rHuCyP-D as determined by LAL method.
Reconstitution
N/A
Category
Others
Background
CyP-D is a part of the peptidyl-prolyl cis-trans isomerase (PPIase) family. CyP-D accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. CyP-D is key component of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.