- ¥1152
- 联迈生物
- LM7257-20μg
- 中国/上海
- 2025年07月10日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
大量
- 英文名：
Recombinant Human Bcl-2
- 保质期：
一年
- 供应商：
上海联迈生物工程有限公司
- 保存条件：
-20℃或更低温度保存
- 规格：
20μg
| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| LM7257-20μg | Recombinant Human Bcl-2 | 20μg | 1152.00元 |
| Species | Gene ID | Accession | Source | Length | MW | Tag |
| Human | 596 | LM10415 | E. coli | 210aa | 23kDa | － |
| About this Antibody | |
| Name | Recombinant Human Bcl-2 (Recombinant Human B-cell Lymphoma 2; rHuBcl-2)；重组人B细胞淋巴瘤2 |
| Synonyms | apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; Bcl-2 |
| Purity | >95% by SDS-PAGE and HPLC analyses. |
| Biological Activity | Test in Process. |
| Physical Appearance | Sterile liquid. |
| Formulation | 0.2μm filtered concentrated solution in 25mM Tris-HCl, pH8.0, 100mM NaCl, 1mM DTT, 30% Glycerol, with Tween-80. |
| Endotoxin | Less than 0.1EU/μg of rHuBcl-2 as determined by LAL method. |
| Reconstitution | N/A |
| Category | Others |
| Background | B-cell lymphoma 2 (Bcl-2) is the founding member of the Bcl-2 family and it is encoded by the BCL2 gene in human. Bcl-2 forms homodimer and heterodimers with other Bcl-2 family proteins, like BAX, BAK, BAD and Bcl-xL. Alternative splicing of Bcl-2 results in two isoforms with similar folds despite differences in anti-apoptotic activity. Bcl-2 suppresses apoptosis by controlling the mitochondrial membrane permeability. It inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Antibodies to Bcl-2 can be used with immunohistochemistry to identify cells containing the antigen. In some cases, the presence or absence of Bcl-2 staining in biopsies may be significant for the patient's prognosis or likelihood of cancer relapse. Mature human Bcl-2 shares 88%-90% amino acid sequence identity with murine, rat, bovine, canine Bcl-2. |
| Amino Acid Sequence | AHAGRTGYDN REIVMKYIHY KLSQRGYEWD AGDVGAAPPG AAPAPGIFSS QPGHTPHPAA SRDPVARTSP LQTPAAPGAA AGPALSPVPP VVHLTLRQAG DDFSRRYRRD FAEMSSQLHL TPFTARGRFA TVVEELFRDG VNWGRIVAFF EFGGVMCVES VNREMSPLVD NIALWMTEYL NRHLHTWIQD NGGWDAFVEL YGPSMRPLFD |
| 产品编号 | 产品名称 | 包装 |
| LM7257-5μg | Recombinant Human Bcl-2 | 5μg |
| LM7257-20μg | Recombinant Human Bcl-2 | 20μg |
| LM7257-100μg | Recombinant Human Bcl-2 | 100μg |
| LM7257-1mg | Recombinant Human Bcl-2 | 1mg |
| - | 说明书 | 1份 |
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
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