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- 英国
- abx066195
- 2025年11月20日
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- 文献和实验
- 技术资料
- 保存条件：
参照说明书
- 英文名：
Rat Cyclin D1 (CCND1) Protein
- 供应商：
北京博蕾德生物科技有限公司
- 规格：
10 μg///50 μg///100 μg
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文献和实验Promoter-Associated Noncoding RNA from the CCND1 Promoter
Biol Chem 276:6807–6816, 2001). TLS is specifically recruited to the CBP/p300-associated binding sites of the cyclin D1 gene (CCND1 ) and the cyclin E1 gene (CCNE1 ) promoters (Wang et al., Nature 454:126–130, 2008; Impey et al., Cell 119:1041–1054
Disorders of the cell cycle regulatory machinery play a key role in the pathogenesis of cancer. The gene encoding the cyclin D1 protein, a regulator of the progression from the G1- to S-phase, is often found disrupted in the cancer cell
Induction of Tumor Cell Apoptosis and Chemosensitization by Antisense Strategies
in tumor cells in synergy with other anticancer agents. In contrast to the low basal levels of the mitogen-dependent cyclin D1 and of the DNA-damage-inducible p53 tumor suppressor protein, tumors with greater genetic instability and poor therapeutic
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