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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
4°C, stored under nitrogen
- 英文名：
Frambione; 4-(4-Hydroxyphenyl)-2-butanone
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
5471-51-2
- 规格：
10 mM * 1 mL/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥550.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥500.0 |
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Raspberry ketone
CAS No. : 5471-51-2
MCE 国际站：Raspberry ketone
产品活性：Raspberry ketone 是覆盆子中主要的芳香族化合物，主要用作化妆品的香料和食品增味剂；同时可作为 PPAR-α 的激动剂起作用。
研究领域：Cell Cycle/DNA Damage | Vitamin D Related/Nuclear Receptor
作用靶点：PPAR
In Vitro: Raspberry ketone (1, 10, 20, and 50 μM) suppresses adipogenesis and lipid accumulation in 3T3-L1 pre-adipocytes. Raspberry ketone (10 µM) significantly blocks C/EBPα, PPARγ, and aP2 expression and increases the expression of ATGL and HSL, and CPT1B.
In Vivo: Raspberry ketone (0.5%, 1%, or 2%) increasses the levels of total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol contents (LDL-C), ISI (insulin-sensitivr index), PPAR-α and LDLR, decreases the serum levels of AST (aspartate aminotransferase), ALT (alanine aminotransferase), ALP (alkaline phosphatase), IRI (insulin resistance index), GLU (glucose), INS (insulin-sensitivr index), LEP (leptin), and TNF-α in rats compared with a high-fat diet-induced NASH model. Raspberry ketone also causes increased SOD activities. Raspberry ketone shows cardioprotective action against isoproterenol-induced myocardial infarction in rats, and the effects may be due to its PPAR-α agonistic activity.
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文献和实验亦称丙酮体。是乙酰乙酸、 D-3-羟基丁酸、丙酮三者的总称。肝脏将由脂肪酸或丙酮酸氧化生成的过剩的乙酰辅酶 A转变为乙酰乙酸和 D-3-羟基丁酸送至血液中。这些酮体在末梢组织中经三羧酸循环而进行代谢。在正常的情况下，血中的酮体浓度是低的，通常换算成丙酮不超过 1毫克／ 100毫升。人尿中排出量每天为 1毫克。饥饿或患糖尿病时，可形成大量酮体，从血液中的浓度和尿中的排出量的增加来看，这种状态被称ⅰ８文谝阴Ｒ宜岬纳扇缤妓荆蔷?/FONT>3-羟基 -3-甲基
Studies of protein structure and function using single-molecule fluorescence resonance energy transfer (smFRET) benefit dramatically from the ability to site-specifically label proteins with small fluorescent dyes. Genetically encoding
Identification of Phytophthora fragariae var. rubi by PCR
The following chapter describes a PCR method for the identification of the raspberry root rot pathogen Phytophthora fragariae var. rubi . Furthermore, a nested PCR suitable for the detection of the pathogen in infected raspberry roots
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