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VivaCell货号C3801-0100去外泌体胎牛血清(无

外泌体胎牛血清)13611631389上海睿安生物
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  • ￥5040.01
  • VivaCell
  • C3801-0100
  • made in China
  • 2025年10月18日
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    上海睿安生物科技有限公司
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    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 库存：

      1000⁺瓶

    • 英文名：

      Exosome Depleted Fetal Bovine Serum

    • 保质期：

      5年

    • 供应商：

      上海睿安生物13611631389

    • 保存条件：

      -20°C

    • 规格：

      100ml/瓶

    VivaCell货号C3801-0100去外泌体胎牛血清(无外泌体胎牛血清)13611631389上海睿安生物

    VivaCell货号C3801-0100去外泌体胎牛血清(无外泌体胎牛血清)Exosome Depleted Fetal Bovine Serum上海睿安生物13611631389

    【产品说明】

    • 第二代去外泌体胎牛血清

    • 由无菌采集的健康胎牛血清过滤而成

    • 符合CGMP 生产要求

    • 去除≥99% 的胎牛血清内源外泌体

    • 细胞可维持与正常胎牛血清中相同生长速率和形态

    • 在进行外泌体研究中，如果是从细胞培养上清中获取外泌体以进行后续研究，需避免使用常规胎牛血清或使用无血清培养系统。因为胎牛血清中含有大量牛源外泌体，会严重干扰实验。因此，建议在细胞培养过程中，使用去外泌体血清，保证后续实验的准确性。

    【数据说明】

    产品细节图片1

            图1：A549在常规胎牛血清和去外泌体血清中生长情况基本一致。

     

     

    产品细节图片2

                        图2：NTA数据显示去外泌体血清已基本去除外泌体。

                        （FBS：常规胎牛血清，Exo-FBS：去外泌体血清）

     

                       产品细节图片3

    图3：β-actin 为内参, 相比于未处理的血清, 去外泌体血清的 TSG101 含量极低。

                        （FBS：常规胎牛血清，Exo-FBS：去外泌体血清）

     

    【注意事项】

    如有一下情形，请勿使用

    1、试剂包装有破损

    2、溶液浑浊，有被污染的可能

    3、使用时已超过规定有效期

    【储存条件及保质期】应储存在-10~-20℃，无自动化霜冰箱中。有效期为5年。

    产品细节图片4

    产品细节图片5产品细节图片6

    VivaCell去外泌体血清已发表文章列表-文献(更新于2020-12-31 10:40)

    1. Liu Y, Lou G, Li A, et al. AMSC-derived exosomes alleviate lipopolysaccharide/d-galactosamine-induced acute liver failure by miR-17-mediated reduction of TXNIP/NLRP3 inflammasome activation in macrophages. EBioMedicine. 2018 Oct;36:140-150. IF: 6.183.

    2. Xu BF, Wang QQ, Zhang JP, et al. Treponema pallidum induces the activation of endothelial cells via macrophage-derived exosomes. Arch Dermatol Res. 2019 Mar;311(2):121-130. IF: 2.148.

    3. Zhou Q, Lian Y, Zhang Y, et al. Platelet-derived microparticles from recurrent miscarriage associated with antiphospholipid antibody syndrome influence behaviours of trophoblast and endothelial cells. Mol Hum Reprod. 2019 Aug 1;25(8):483-494. IF: 3.396.

    4. Wei Z, Qiao S, Zhao J, et al. miRNA-181a over-expression in mesenchymal stem cell-derived exosomes influenced inflammatory response after myocardial ischemia-reperfusion injury. Life Sci. 2019 Sep 1;232:116632. IF: 3.448.

    5. Zhou X, Wang W, Cui F, et al. Extracellular vesicles derived from Echinococcus granulosus hydatid cyst fluid from patients: isolation, characterization and evaluation of immunomodulatory functions on T cells. Int J Parasitol. 2019 Dec;49(13-14):1029-1037. IF: 3.478.

    6. Yin X, Hou T, Huang B, et al. Aptamer recognition-trigged label-free homogeneous electrochemical strategy for an ultrasensitive cancer-derived exosome assay. Chem Commun (Camb). 2019 Nov 12;55(91):13705-13708. IF: 6.164.

    7. Li B, Zang G, Zhong W, et al. Activation of CD137 signaling promotes neointimal formation by attenuating TET2 and transferrring from endothelial cell-derived exosomes to vascular smooth muscle cells. Biomed Pharmacother. 2020 Jan;121:109593. IF: 3.743.

    8. Hu W, Xu B, Zhang J, et al. Exosomal miR-146a-5p from Treponema pallidum-stimulated macrophages reduces endothelial cells permeability and monocyte transendothelial migration by targeting JAM-C. Exp Cell Res. 2020 Mar 1;388(1):111823. IF: 3.383.

    9. Han M, Hu J, Lu P, et al. Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer. Cell Death Dis. 2020 Jan 22;11(1):43. IF: 5.959.

    10. Liu S, Chen J, Shi J, et al. M1-like macrophage-derived exosomes suppress angiogenesis and exacerbate cardiac dysfunction in a myocardial infarction microenvironment. Basic Res Cardiol. 2020 Feb 28;115(2):22. IF: 11.981.

    11. Qiao S, Zhang W, Yin Y, et al. Extracellular vesicles derived from Krüppel-Like Factor 2-overexpressing endothelial cells attenuate myocardial ischemia-reperfusion injury by preventing Ly6Chigh monocyte recruitment. Theranostics. 2020 Sep 18;10(25):11562-11579. IF: 8.579.

    12. Zhou W, Zheng X, Cheng C, et al. Rab27a deletion impairs the therapeutic potential of endothelial progenitor cells for myocardial infarction. Mol Cell Biochem. 2021 Feb;476(2):797-807. IF: 2.795.

    13. Liu H, Liu Y, Sun P, et al. Colorectal cancer-derived exosomal miR-106b-3p promotes metastasis by down-regulating DLC-1 expression. Clin Sci (Lond). 2020 Feb 28;134(4):419-434.  IF: 5.223.

    14. Chen J, Chen J, Cheng Y, et al. Mesenchymal stem cell-derived exosomes protect beta cells against hypoxia-induced apoptosis via miR-21 by alleviating ER stress and inhibiting p38 MAPK phosphorylation. Stem Cell Res Ther. 2020 Mar 4;11(1):97. IF: 5.116.

    15. Wang Y, Lu J, Chen L, et al. Tumor-Derived EV-Encapsulated miR-181b-5p Induces Angiogenesis to Foster Tumorigenesis and Metastasis of ESCC. Mol Ther Nucleic Acids. 2020 Jun 5;20:421-437. IF: 7.032.

    16. Gao X, Xiong Y, Li Q, et al. Extracellular vesicle-mediated transfer of miR-21-5p from mesenchymal stromal cells to neurons alleviates early brain injury to improve cognitive function via the PTEN/Akt pathway after subarachnoid hemorrhage. Cell Death Dis. 2020 May 13;11(5):363. IF: 6.304.

    17. Yuan HX, Chen CY, Li YQ, et al. Circulating extracellular vesicles from patients with valvular heart disease induce neutrophil chemotaxis via FOXO3a and the inhibiting role of dexmedetomidine. Am J Physiol Endocrinol Metab. 2020 Jul 1;319(1):E217-E231. IF: 3.469.

    18. Zhao Q, Zheng X, Guo H, et al. Serum Exosomal miR-941 as a promising Oncogenic Biomarker for Laryngeal Squamous Cell Carcinoma. J Cancer. 2020 Jul 9;11(18):5329-5344. IF: 3.565.

    19. Zhao X, Li M, Dai X, et al. Downregulation of exosomal miR‑1273a increases cisplatin resistance of non‑small cell lung cancer by upregulating the expression of syndecan binding protein. Oncol Rep. 2020 Nov;44(5):2165-2173. IF: 3.417.

    20. Liu, et al. The in vitro osteogenesis induction by a nano-hydroxyapatite composite that combined with miRNA-27b overexpression exosomes. Aging. 2020.  IF: 5.515.

    21. Xie L, Guan Z, Zhang M, et al. Exosomal circLPAR1 Promoted Osteogenic Differentiation of Homotypic Dental Pulp Stem Cells by Competitively Binding to hsa-miR-31. Biomed Res Int. 2020 Sep 28;2020:6319395.  IF: 2.276.

    22. Zhang C, Wang H, Chan GCF, et al. Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stromal Cells Protect Cardiac Cells Against Hypoxia/Reoxygenation Injury by Inhibiting Endoplasmic Reticulum Stress via Activation of the PI3K/Akt Pathway. Cell Transplant. 2020 Jan-Dec;29:963689720945677.  IF: 3.341.

    23. Yu L, Sui B, Fan W, et al. Exosomes derived from osteogenic tumor activate osteoclast differentiation and concurrently inhibit osteogenesis by transferring COL1A1-targeting miRNA-92a-1-5p. J Extracell Vesicles. 2021 Jan;10(3):e12056.  IF: 14.976.

    24. Xie L, Chen J, Ren X, et al. Alteration of circRNA and lncRNA expression profile in exosomes derived from periodontal ligament stem cells undergoing osteogenic differentiation. Arch Oral Biol. 2021 Jan;121:104984. IF: 2.633.

    25. Zhang A, Bai Z, Yi W, et al. Overexpression of miR-338-5p in exosomes derived from mesenchymal stromal cells provides neuroprotective effects by the Cnr1/Rap1/Akt pathway after spinal cord injury in rats. Neurosci Lett. 2021 Jul 22;761:136124.  IF: 3.046.

    26. Li, et al. Exosomes from human urine-derived stem cells ameliorate particulate polyethylene-induced osteolysis. Research Square. 2021.

    27. Hu Y, Wu B, Xiong Y, et al. Cryogenic 3D printed hydrogel scaffolds loading exosomes accelerate diabetic wound healing. Chemical Engineering Journal. 2021；426:130634. IF: 13.273.

    28. Liu, et al. Hepatocyte-derived exosomal microRNAs orchestrate vascular inammation and endothelial function: insights into molecular mechanisms of trimethylamine-N-Oxide in atherosclerosis. Research Square. 2021.

    29. Hu Y, Tao R, Chen L, et al. Exosomes derived from pioglitazone-pretreated MSCs accelerate diabetic wound healing through enhancing angiogenesis. J Nanobiotechnology. 2021 May 21;19(1):150. IF: 10.435.

    30. Deng Z, Wang J, Xiao Y, et al. Ultrasound-mediated augmented exosome release from astrocytes alleviates amyloid-β-induced neurotoxicity. Theranostics. 2021 Feb 25;11(9):4351-4362. IF: 8.579.产品细节图片7产品细节图片8产品细节图片9

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    • 作者
    • 内容
    • 询问日期
    图标文献和实验
    该产品被引用文献

    VivaCell货号C3801-0100去外泌体胎牛血清(无外泌体胎牛血清)13611631389上海睿安生物

    VivaCell货号C3801-0100去外泌体胎牛血清(无外泌体胎牛血清)Exosome Depleted Fetal Bovine Serum上海睿安生物13611631389

    【产品说明】

    • 第二代去外泌体胎牛血清

    • 由无菌采集的健康胎牛血清过滤而成

    • 符合CGMP 生产要求

    • 去除≥99% 的胎牛血清内源外泌体

    • 细胞可维持与正常胎牛血清中相同生长速率和形态

    • 在进行外泌体研究中，如果是从细胞培养上清中获取外泌体以进行后续研究，需避免使用常规胎牛血清或使用无血清培养系统。因为胎牛血清中含有大量牛源外泌体，会严重干扰实验。因此，建议在细胞培养过程中，使用去外泌体血清，保证后续实验的准确性。

    【数据说明】

    引用文献图片1

            图1：A549在常规胎牛血清和去外泌体血清中生长情况基本一致。

     

     

    引用文献图片2

                        图2：NTA数据显示去外泌体血清已基本去除外泌体。

                        （FBS：常规胎牛血清，Exo-FBS：去外泌体血清）

     

                       引用文献图片3

    图3：β-actin 为内参, 相比于未处理的血清, 去外泌体血清的 TSG101 含量极低。

                        （FBS：常规胎牛血清，Exo-FBS：去外泌体血清）

     

    【注意事项】

    如有一下情形，请勿使用

    1、试剂包装有破损

    2、溶液浑浊，有被污染的可能

    3、使用时已超过规定有效期

    【储存条件及保质期】应储存在-10~-20℃，无自动化霜冰箱中。有效期为5年。

    引用文献图片4

    引用文献图片5引用文献图片6

    VivaCell去外泌体血清已发表文章列表-文献(更新于2020-12-31 10:40)

    1. Liu Y, Lou G, Li A, et al. AMSC-derived exosomes alleviate lipopolysaccharide/d-galactosamine-induced acute liver failure by miR-17-mediated reduction of TXNIP/NLRP3 inflammasome activation in macrophages. EBioMedicine. 2018 Oct;36:140-150. IF: 6.183.

    2. Xu BF, Wang QQ, Zhang JP, et al. Treponema pallidum induces the activation of endothelial cells via macrophage-derived exosomes. Arch Dermatol Res. 2019 Mar;311(2):121-130. IF: 2.148.

    3. Zhou Q, Lian Y, Zhang Y, et al. Platelet-derived microparticles from recurrent miscarriage associated with antiphospholipid antibody syndrome influence behaviours of trophoblast and endothelial cells. Mol Hum Reprod. 2019 Aug 1;25(8):483-494. IF: 3.396.

    4. Wei Z, Qiao S, Zhao J, et al. miRNA-181a over-expression in mesenchymal stem cell-derived exosomes influenced inflammatory response after myocardial ischemia-reperfusion injury. Life Sci. 2019 Sep 1;232:116632. IF: 3.448.

    5. Zhou X, Wang W, Cui F, et al. Extracellular vesicles derived from Echinococcus granulosus hydatid cyst fluid from patients: isolation, characterization and evaluation of immunomodulatory functions on T cells. Int J Parasitol. 2019 Dec;49(13-14):1029-1037. IF: 3.478.

    6. Yin X, Hou T, Huang B, et al. Aptamer recognition-trigged label-free homogeneous electrochemical strategy for an ultrasensitive cancer-derived exosome assay. Chem Commun (Camb). 2019 Nov 12;55(91):13705-13708. IF: 6.164.

    7. Li B, Zang G, Zhong W, et al. Activation of CD137 signaling promotes neointimal formation by attenuating TET2 and transferrring from endothelial cell-derived exosomes to vascular smooth muscle cells. Biomed Pharmacother. 2020 Jan;121:109593. IF: 3.743.

    8. Hu W, Xu B, Zhang J, et al. Exosomal miR-146a-5p from Treponema pallidum-stimulated macrophages reduces endothelial cells permeability and monocyte transendothelial migration by targeting JAM-C. Exp Cell Res. 2020 Mar 1;388(1):111823. IF: 3.383.

    9. Han M, Hu J, Lu P, et al. Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer. Cell Death Dis. 2020 Jan 22;11(1):43. IF: 5.959.

    10. Liu S, Chen J, Shi J, et al. M1-like macrophage-derived exosomes suppress angiogenesis and exacerbate cardiac dysfunction in a myocardial infarction microenvironment. Basic Res Cardiol. 2020 Feb 28;115(2):22. IF: 11.981.

    11. Qiao S, Zhang W, Yin Y, et al. Extracellular vesicles derived from Krüppel-Like Factor 2-overexpressing endothelial cells attenuate myocardial ischemia-reperfusion injury by preventing Ly6Chigh monocyte recruitment. Theranostics. 2020 Sep 18;10(25):11562-11579. IF: 8.579.

    12. Zhou W, Zheng X, Cheng C, et al. Rab27a deletion impairs the therapeutic potential of endothelial progenitor cells for myocardial infarction. Mol Cell Biochem. 2021 Feb;476(2):797-807. IF: 2.795.

    13. Liu H, Liu Y, Sun P, et al. Colorectal cancer-derived exosomal miR-106b-3p promotes metastasis by down-regulating DLC-1 expression. Clin Sci (Lond). 2020 Feb 28;134(4):419-434.  IF: 5.223.

    14. Chen J, Chen J, Cheng Y, et al. Mesenchymal stem cell-derived exosomes protect beta cells against hypoxia-induced apoptosis via miR-21 by alleviating ER stress and inhibiting p38 MAPK phosphorylation. Stem Cell Res Ther. 2020 Mar 4;11(1):97. IF: 5.116.

    15. Wang Y, Lu J, Chen L, et al. Tumor-Derived EV-Encapsulated miR-181b-5p Induces Angiogenesis to Foster Tumorigenesis and Metastasis of ESCC. Mol Ther Nucleic Acids. 2020 Jun 5;20:421-437. IF: 7.032.

    16. Gao X, Xiong Y, Li Q, et al. Extracellular vesicle-mediated transfer of miR-21-5p from mesenchymal stromal cells to neurons alleviates early brain injury to improve cognitive function via the PTEN/Akt pathway after subarachnoid hemorrhage. Cell Death Dis. 2020 May 13;11(5):363. IF: 6.304.

    17. Yuan HX, Chen CY, Li YQ, et al. Circulating extracellular vesicles from patients with valvular heart disease induce neutrophil chemotaxis via FOXO3a and the inhibiting role of dexmedetomidine. Am J Physiol Endocrinol Metab. 2020 Jul 1;319(1):E217-E231. IF: 3.469.

    18. Zhao Q, Zheng X, Guo H, et al. Serum Exosomal miR-941 as a promising Oncogenic Biomarker for Laryngeal Squamous Cell Carcinoma. J Cancer. 2020 Jul 9;11(18):5329-5344. IF: 3.565.

    19. Zhao X, Li M, Dai X, et al. Downregulation of exosomal miR‑1273a increases cisplatin resistance of non‑small cell lung cancer by upregulating the expression of syndecan binding protein. Oncol Rep. 2020 Nov;44(5):2165-2173. IF: 3.417.

    20. Liu, et al. The in vitro osteogenesis induction by a nano-hydroxyapatite composite that combined with miRNA-27b overexpression exosomes. Aging. 2020.  IF: 5.515.

    21. Xie L, Guan Z, Zhang M, et al. Exosomal circLPAR1 Promoted Osteogenic Differentiation of Homotypic Dental Pulp Stem Cells by Competitively Binding to hsa-miR-31. Biomed Res Int. 2020 Sep 28;2020:6319395.  IF: 2.276.

    22. Zhang C, Wang H, Chan GCF, et al. Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stromal Cells Protect Cardiac Cells Against Hypoxia/Reoxygenation Injury by Inhibiting Endoplasmic Reticulum Stress via Activation of the PI3K/Akt Pathway. Cell Transplant. 2020 Jan-Dec;29:963689720945677.  IF: 3.341.

    23. Yu L, Sui B, Fan W, et al. Exosomes derived from osteogenic tumor activate osteoclast differentiation and concurrently inhibit osteogenesis by transferring COL1A1-targeting miRNA-92a-1-5p. J Extracell Vesicles. 2021 Jan;10(3):e12056.  IF: 14.976.

    24. Xie L, Chen J, Ren X, et al. Alteration of circRNA and lncRNA expression profile in exosomes derived from periodontal ligament stem cells undergoing osteogenic differentiation. Arch Oral Biol. 2021 Jan;121:104984. IF: 2.633.

    25. Zhang A, Bai Z, Yi W, et al. Overexpression of miR-338-5p in exosomes derived from mesenchymal stromal cells provides neuroprotective effects by the Cnr1/Rap1/Akt pathway after spinal cord injury in rats. Neurosci Lett. 2021 Jul 22;761:136124.  IF: 3.046.

    26. Li, et al. Exosomes from human urine-derived stem cells ameliorate particulate polyethylene-induced osteolysis. Research Square. 2021.

    27. Hu Y, Wu B, Xiong Y, et al. Cryogenic 3D printed hydrogel scaffolds loading exosomes accelerate diabetic wound healing. Chemical Engineering Journal. 2021；426:130634. IF: 13.273.

    28. Liu, et al. Hepatocyte-derived exosomal microRNAs orchestrate vascular inammation and endothelial function: insights into molecular mechanisms of trimethylamine-N-Oxide in atherosclerosis. Research Square. 2021.

    29. Hu Y, Tao R, Chen L, et al. Exosomes derived from pioglitazone-pretreated MSCs accelerate diabetic wound healing through enhancing angiogenesis. J Nanobiotechnology. 2021 May 21;19(1):150. IF: 10.435.

    30. Deng Z, Wang J, Xiao Y, et al. Ultrasound-mediated augmented exosome release from astrocytes alleviates amyloid-β-induced neurotoxicity. Theranostics. 2021 Feb 25;11(9):4351-4362. IF: 8.579.引用文献图片7引用文献图片8引用文献图片9

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