北京重组人TNFα(TNFSF2)促销

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产销*(代"售")北京重组人TNFα(TNFSF2)促销，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：重组人TNFα(TNFSF2)
产地：国产|进口
品牌：百奥莱博
编号：JN0438
本品由我们的大肠杆菌表达系统制备而成。

TNFa/TNFSF2 (high active)质量控制：＞95%(还原性SDS-PAGE)


TNFa/TNFSF2 (high active)制剂：冻干品

TNFa/TNFSF2 (high active)保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TNFa/TNFSF2 (high active)复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TNFa/TNFSF2 (high active)：
Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-α while cells that express CD8 secrete little or no TNF-α. Synthesis of TNF-α can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumor activity of TNF-α has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF-α mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF-α that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumor activity and reduced systemic toxicity in mice comp*(代"a")red with murine TNF-α, which binds to both murine TNF receptors. Based on these results, many TNF-α mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumor cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF-α High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.

关键词：JN0438,重组人TNFSF2,重组人TNFα,重组人TNFα蛋白,重组TNFα


关于北京重组人TNFα(TNFSF2)促销的更详细说明，请致电我公司咨询，我们将以最饱满的热情为您提供解答，此外，我公司专业供应下列产品：

 

编号	名称
JN1667	重组人SENP8
JN1892	重组小鼠CD33(Siglec-3)
JN1397	重组人血红蛋白θ1(HBQ1)
JN0272	重组人成纤维生长因子8e
JN0922	重组人α-Parvin(PARVA)
JN0895	重组人NIP7
JN1773	重组小鼠SLAMF6(CD352)
JN0134	肌酸酶
JN1199	重组人铁蛋白重链(FTH1)(N端带His标签)
JN1459	重组小鼠TIM-3
JN1544	重组人吲哚胺-2,3双加氧酶(IDO)
JN0757	重组人乳铁传递蛋白(LTF)(乳运铁蛋白)
JN2018	重组人磷酸甲羟戊酸激酶(PMVK)
JN1038	重组人降*素(CALCA)
JN1362	重组人DCBLD2
JN1603	重组Cutinase
JN1477	重组人Serpin B3(SSCA1)(丝*酸蛋白酶抑制剂B3)
JN1388	重组人ECH1
JN0391	重组人白介素IL-2(白细胞介素2)
JN0915	重组人PLA2G16(磷脂酶A2-XVI)
JN1674	重组人Cystatin F(胱抑素F)
JN1145	重组人Txndc4(Erp44)
JN1853	重组人CLEC10A
JN1735	重组人TMPRSS11B
JN0075	DNA聚合酶I(大肠杆菌)
JN1536	重组人CD66E(CEACAM5)(癌胚抗原相关细胞粘附分子5)
JN0594	重组人Tie-1
JN1928	重组人Esterase D
JN0470	重组人4-1BBL(TNFSF9)
JN1910	重组人BCL2L1(Bcl-Xl)
JN1542	重组TIGIT
JN1054	重组人FKBP4(52kDa FK506结合蛋白)
JN0038	2×Hot Start Taq PCR MasterMix
JN1198	重组人铁蛋白轻链(FTL)
JN0246	重组人VEGF121(血管内皮生长因子121)
JN1835	重组人CEACAM1(CD66a)
JN1289	重组人Chemerin(视黄酸受体反应蛋白2)
JN0947	重组人中性粒细胞明胶酶相关脂质运载蛋白(NGAL)(LCN2)
JN1883	重组人CD83
JN0510	重组小鼠4-1BB Ligand(TNFSF9)